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Home >> Antibodies >> Cytokeratin, Type II (Epithelial Marker)

Cytokeratin, Type II (Epithelial Marker)

Recombinant Mouse Monoclonal Antibody [Clone rKRTH/6617]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

219.00
499.00
499.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

219.00
499.00
499.00
img

Formalin-fixed, paraffin-embedded human sebaceous gland stained with CK Type II Recombinant Mouse Monoclonal Antibody (rKRTH/6617).

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Formalin-fixed, paraffin-embedded human skin stained with CK Type II Recombinant Mouse Monoclonal Antibody (rKRTH/6617).

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SDS-PAGE Analysis Purified CK Type 2 Recombinant Mouse Monoclonal (rKRTH/6617). Confirmation of Purity and Integrity of Antibody.

Product Details

Synonyms

KRT2B; KRT2P; HUMCYT2A; Keratin, type II Cytoskeletal 2 oral; K76; Keratin 2p (K2P); Keratin-76; Cytokeratin-2P (CK-2P; Type-II Keratin Kb9

Positive Control

Skin or squamous cell carcinoma.

Known Applications & Suggested Dilutions

IHC-P         More Details

Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Immunogen

Synthetic peptide corresponding to Type II Cytokeratins residues within aa300-400 of Type II Cytokeratins

Cellular Localization

Cytoplasmic

Species Reactivity

Human.

Host / Ig Isotype

Mouse / IgG1, kappa

Mol. Weight of Antigen

66/65/64/57/62/60/51/54kDa

Specificity & Comments

The keratins are the typical intermediate filament proteins of epithelia, showing an outstanding degree of molecular diversity. Heteropolymeric filaments are formed by pairing of type I and type II molecules. In humans 54 functional keratin genes exist. They are expressed in highly specific patterns related to the epithelial type and stage of cellular differentiation. This antibody can detect high molecular weight CK1, CK2, CK3, CK4, CK5, CK6, CK7 and CK8. It is usually used in a cytokeratin cocktail with type I cytokeratins antibody.

Related Products



200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Spagnolo DV, et al. Am J Clin Pathol. 1985 Dec;84(6):697-704.
  2. Eichner R, et al. J Cell Biol. 1984 Apr;98(4):1388-96.

Bioinformatics

  •  Entrez Gene ID: 51350
  •  Gene Symbol: KRT76
  •  SwissProt: Q01546
  •  Chromosome Location: 12q13.13
  •  Unigene: 654392