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Natural killer (NK) cells are a type of lymphocyte, a white blood cell, that play a crucial role in the innate immune system. They are primarily known for their ability to recognize and destroy infected or cancerous cells without prior sensitization or the need for specific antigens. NK cells are essential for the early defense against infections and tumor surveillance.
NK cell biomarkers distinguish NK cells from other immune cell types, such as T cells or B cells, in blood and tissues, which is essential for studying their roles in immune responses and disease processes. Some of these biomarkers also yield information about the activation and cytotoxicity of these cells. Additionally, NK cell biomarkers can be used to monitor various disease states, including infections, cancer, and autoimmune diseases, and provide prognostic information about disease outcomes, especially in cancer. Furthermore, NK cell biomarkers are relevant to developing cancer immunotherapies that enhance NK cell activity.
The choice of which NK cell biomarkers to measure depends on the specific goals of the analysis and the research context. NeoBiotechnologies offers a variety of validated antibodies targeting NK cell protein biomarkers that are guaranteed to yield accurate and reliable results. A list of our specific and sensitive antibodies and their intended applications is shown in the table below.
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