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Home >> Antibodies >> CD38 (ADP Ribosyl Cyclase I)

CD38 (ADP Ribosyl Cyclase I)

Mouse Monoclonal Antibody [Clone CD38/4328]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

219.00
499.00
499.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

219.00
499.00
499.00
img

IHC analysis of formalin-fixed, paraffin-embedded human tonsil. Strong cytoplasmic and membranous staining using CD38/4328 at 2ug/ml in PBS for 30min RT. HIER: Tris/EDTA, pH9.0, 45min. 2: HRP-polymer, 30min. DAB, 5min.

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IHC analysis of formalin-fixed, paraffin-embedded human prostate carcinoma. Strong cytoplasmic and membranous staining using CD38/4328 at 2ug/ml in PBS for 30min RT. HIER: Tris/EDTA, pH9.0, 45min. 2: HRP-polymer, 30min. DAB, 5min.

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IHC analysis of formalin-fixed, paraffin-embedded human cerebral cortex. Negative tissue control using CD38/4328 at 2ug/ml in PBS for 30min RT. HIER: Tris/EDTA, pH9.0, 45min. 2: HRP-polymer, 30min. DAB, 5min.

img

Western Blot Analysis of Raji cell lysate using CD38 Mouse Monoclonal Antibody (CD38/4328).

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Western blot analysis of human spleen tissue and Raji cell lysates using CD38 Mouse Monoclonal Antibody (CD384328).

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Analysis of Protein Array containing more than 19,000 full-length human proteins using CD38 Mouse Monoclonal Antibody (CD38/4328).

Product Details

Synonyms

Acute Lymphoblastic Leukemia Cells Antigen; ADP Ribosyl Cyclase 1; cADP-ribose Hydrolase 1; CD38H; NAD(+) Nucleosidase; NIM-R5 Antigen; p45; T10

Positive Control

Raji cells. Human tonsil, spleen or skin.

Known Applications & Suggested Dilutions

Flow Cyt, IF, Western Blot, IHC-P         More Details

Flow Cytometry (1-2ug/million cells)
Immunofluorescence (1-2ug/million cells)
Western Blot (2-4ug/ml)
Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)
(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant full-length human CD38 protein

Cellular Localization

Cell surface and cytoplasm

Species Reactivity

Human.

Host / Ig Isotype

Mouse / IgG1, kappa

Mol. Weight of Antigen

~45kDa (Glycoprotein); 35kDa (protein core)

Specificity & Comments

CD38 is a type II transmembrane glycoprotein that is present on early B- and T-cell lineages and activated B- and T-cells but is absent from most mature resting peripheral lymphocytes. CD38 is also found on thymocytes, pre-B cells, germinal center B-cells, mitogen-activated T-cells, monocytes and Ig-secreting plasma cells. CD38 is expressed on CD34+ cells. The CD34+CD38- population of hematopoietic stems cells define the most pluripotent cells (e.g. blast colony forming cells).

Related Products



200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Deaglio S, et. al. J Immunol. 1998;160(1):395-402.

Bioinformatics

  •  Entrez Gene ID: 952
  •  Gene Symbol: CD38
  •  SwissProt: P28907
  •  Chromosome Location: 4p15
  •  Unigene: 479214