SDS-PAGE Analysis Purified CD38 Recombinant Rabbit Monoclonal Antibody (CD38/7017R). Confirmation of Purity and Integrity of Antibody.

Western blot analysis of Raji cell lysate using CD38 Recombinant Rabbit Monoclonal Antibody (CD38/7017R).

Formalin-fixed, paraffin-embedded human tonsil stained with CD38 Recombinant Rabbit Monoclonal Antibody (CD38/7017R). Inset: PBS instead of primary antibody; secondary only negative control.

Formalin-fixed, paraffin-embedded human tonsil stained with CD38 Recombinant Rabbit Monoclonal Antibody (CD38/7017R). HIER: Tris/EDTA, pH9.0, 45min. 2 °: HRP-polymer, 30min. DAB, 5min.

Printable Datasheet

CD38 (ADP Ribosyl Cyclase I) [CD38/7017R]

Name: CD38 (ADP Ribosyl Cyclase I)
SKU: 952-RBM13
Availability: InStock

Monoclonals Primary Antibodies Rabbit Monoclonals Recombinant Rabbit Monoclonals Recombinants

Summary

CD38 is a type II transmembrane glycoprotein that is present on early B- and T-cell lineages and activated B- and T-cells but is absent from most mature resting peripheral lymphocytes. CD38 is found on thymocytes, pre-B cells, germinal center B-cells, mitogen-activated T-cells, monocytes and Ig-secreting plasma cells. CD38 is expressed on CD34+ cells. The CD34+CD38- population of hematopoietic stems cells define the most pluripotent cells (e.g.blast colony forming cells).

Product Properties & Targets

Host

Rabbit

Species Reactivity

Human

Isotype

IgG

Cellular Localization

Membrane

Gene Name

CD38

Mol. Weight of Antigen

~45kDa (Glycoprotein); 35kDa (protein core)

Immunogen

Synthetic peptide corresponding to residues within aa 200-300 of human CD38 (exact sequence is proprietary)

Database Links

Entrez Gene ID

952

Unigene

479214

SwissProt

P28907

Additional Information

Clone

CD38/7017R

Human Gene Symbol

CD38

Chromosome Location

4p15

Known Applications & Suggested Dilutions

Western Blot (1-2ug/ml)
,Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 &degC followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Key References

Deaglio S, et. al. J Immunol. 1998;160(1):395-402.

PubMed Links

Storage & Stability

Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for diagnosis.

Supplied as

200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.