Home >> Antibodies >> LMO2 (B-Cell Marker)

LMO2 (B-Cell Marker)

Mouse Monoclonal Antibody [Clone LMO2/1972]

Printable

Key References

Bioinformatics

Catalog #

Size

20 ug

100 ug

Price (USD)

219.00

499.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml

Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Performance Guarantee

Catalog No

Size

20 ug

100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml

Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

219.00

499.00

Printable

Key References

Bioinformatics

Formalin-fixed, paraffin-embedded human follicular lymphoma stained with LMO2 Mouse Monoclonal Antibody (LMO2/1972).

Formalin-fixed, paraffin-embedded human pancreas stained with LMO2 Mouse Monoclonal Antibody (LMO2/1972).

Formalin-fixed, paraffin-embedded human follicular lymphoma stained with LMO2 Mouse Monoclonal Antibody (LMO2/1972).

Formalin-fixed, paraffin-embedded human pancreas stained with LMO2 Mouse Monoclonal Antibody (LMO2/1972).

Product Details

Synonyms

Cysteine-rich protein TTG-2; LIM domain only protein 2; LMO-2; RBTN L1; RBTN2;Rhombotinlike 1; Rhombotin-2 (RHOM2); T-cell translocation protein 2; TTG2

Positive Control

K562, Ramos or Raji cells.Placenta,pancreas or Hodgkin s lymphoma

Known Applications & Suggested Dilutions

IHC-P More Details

Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)
(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant human LMO2 protein fragment (around aa 23-140) (exact sequence is proprietary)

Cellular Localization

Nucleus. Cytoplasm. Cell surface.

Species Reactivity

Human.

Host / Ig Isotype

Mouse / IgG2b, kappa

Mol. Weight of Antigen

24kDa

Specificity & Comments

The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. It has a particular function in normal and lymphatic endothelial cells involving the regulation of angiogenesis and lymph-angiogenesis. Immunohistochemical studies have also demonstrated expression of LMO2 in both normal germinal center B-cells and germinal center-derived B-cell lymphomas, including follicular lymphoma and diffuse large B-cell lymphoma.The use of anti-LMO2 is valuable as a tool in the identification of lymphomas of B-cell origin.LMO2 is useful in differentiating follicular lymphoma (LMO2+) from nodal marginal zone lymphoma (LM02-). It also is positive in Hodgkin s and Burkitt s lymphomas.