Immunofluorescence staining of K562 cells using LMO2 Recombinant Rabbit Monoclonal Antibody (LMO2/3147R) followed by goat anti-rabbit IgG-CF488 (green). Membrane stained with Phalloidin (Red).

Flow Cytometric Analysis of K562 cells using LMO2 Recombinant Rabbit Monoclonal Antibody (LMO2/3147R); followed by goat anti-rabbit IgG-CF488 (Blue); Isotype Control (Red).

SDS-PAGE Analysis Purified LMO2 Recombinant Rabbit Monoclonal Antibody (LMO2/3147R). Confirmation of Purity and Integrity of Antibody.

LMO2 (B-Cell Marker) [LMO2/3147R]

Name: LMO2 (B-Cell Marker)
SKU: 4005-RBM3
Availability: InStock

Monoclonals Primary Antibodies Rabbit Monoclonals Recombinant Rabbit Monoclonals Recombinants

Summary

The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. It has a particular function in normal and lymphatic endothelial cells involving the regulation of angiogenesis and lymph-angiogenesis. Immunohistochemical studies have also demonstrated expression of LMO2 in both normal germinal center B-cells and germinal center-derived B-cell lymphomas, including follicular lymphoma and diffuse large B-cell lymphoma.The use of anti-LMO2 is valuable as a tool in the identification of lymphomas of B-cell origin. LMO2 is useful in differentiating follicular lymphoma (LMO2+) from nodal marginal zone lymphoma (LM02-). It also is positive in Hodgkin s and Burkitt s lymphomas.

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Product Properties & Targets

Host

Rabbit

Species Reactivity

Human

Isotype

IgG

Cellular Localization

Nucleus

Gene Name

LMO2

Mol. Weight of Antigen

24kDa

Immunogen

Recombinant fragment (around aa 23-140) human LMO2 protein (exact sequence is proprietary)

Database Links

Entrez Gene ID

4005

Unigene

34560

SwissProt

P25791

Additional Information

Clone

LMO2/3147R

Human Gene Symbol

LMO2

Chromosome Location

11p13

Known Applications & Suggested Dilutions

Flow Cytometry (1-2ug/million cells)
,Immunofluorescence (1-2ug/ml)
,Optimal dilution for a specific application should be determined.

Key References

Younes, SF et al. Am J Clin Pathol. 2011 May;135(5):697-708.

PubMed Links

Storage & Stability

Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.