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Home >> Antibodies >> ALDH1A1 (Aldehyde Dehydrogenase 1A1)

ALDH1A1 (Aldehyde Dehydrogenase 1A1)

Recombinant Mouse Monoclonal Antibody [Clone rALDH1A1/7285]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

219.00
499.00
499.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

219.00
499.00
499.00
img

Formalin-fixed, paraffin-embedded human lung stained with ALDH1A1 Recombinant Mouse Monoclonal Antibody (rALDH1A1/7285). HIER: Tris/EDTA, pH9.0, 45min. 2: HRP-polymer, 30min. DAB, 5min.

img

Formalin-fixed, paraffin-embedded human lung stained with ALDH1A1 Recombinant Mouse Monoclonal Antibody (rALDH1A1/7285). Inset: PBS instead of primary antibody; secondary only negative control.

Product Details

Synonyms

AHD2; ALDC; Aldehyde dehydrogenase 1 soluble; ALDH-E1; epididymis luminal protein 12; epididymis luminal protein 9; epididymis secretory sperm binding protein Li53e; HEL-S-53e; PUMB1; RALDH1; Retinal dehydrogenase 1

Positive Control

K562, HepG2 or A549 cells. Human colon or testicular carcinoma.

Known Applications & Suggested Dilutions

IHC-P         More Details

Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)
(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant fragment (around aa 315-434) of human ALDH1A1 protein (exact sequence is proprietary).

Cellular Localization

Cytoplasm.

Species Reactivity

Human.

Host / Ig Isotype

Mouse / IgG1, kappa

Mol. Weight of Antigen

56kDa

Specificity & Comments

ALDH1A1 belongs to the ALDH enzymes, a family of evolutionarily conserved enzymes comprised of 19 isoforms that are localized in the cytoplasm, mitochondria or nucleus. ALDH1A1 is predominantly expressed in the epithelium of testis, brain, eye, liver, kidney, as well as neural and hematopoietic stem cells. Reportedly, high ALDH1A1 expression is found in solitary fibrous tumor (SFT) and hemangiopericytoma (HPC), compared to meningiomas and synovial sarcomas. In combination with CD34, ALDH1A1 may be useful for the differentiation among SFT, HPC, meningioma, and synovial sarcoma.

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200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Bioinformatics

  •  Entrez Gene ID: 216
  •  Gene Symbol: ALDH1A1
  •  SwissProt: P00352
  •  Chromosome Location: 9q21.13
  •  Unigene: 76392