SDS-PAGE Analysis Purified ALDH1A1 Recombinant Rabbit Monoclonal (ALDH1A1/7011R). Confirmation of Integrity and Purity of Antibody.

Formalin-fixed, paraffin-embedded human kidney stained with ALDH1A1 Recombinant Rabbit Monoclonal Antibody (ALDH1A1//7011R). HIER: Tris/EDTA, pH9.0, 45min. 2 °: HRP-polymer, 30min. DAB, 5min.

Formalin-fixed, paraffin-embedded human brain stained with ALDH1A1 Recombinant Rabbit Monoclonal Antibody (ALDH1A1/7011R). Inset: PBS instead of primary antibody; secondary only negative control.

ALDH1A1 (Aldehyde Dehydrogenase 1A1) [ALDH1A1/7011R]

Name: ALDH1A1 (Aldehyde Dehydrogenase 1A1)
SKU: 216-RBM4
Availability: InStock

Monoclonals Primary Antibodies Rabbit Monoclonals Recombinant Rabbit Monoclonals Recombinants

Summary

ALDH1A1 belongs to the ALDH enzymes, a family of evolutionarily conserved enzymes comprised of 19 isoforms that are localized in the cytoplasm, mitochondria or nucleus. ALDH1A1 is predominantly expressed in the epithelium of testis, brain, eye, liver, kidney, as well as neural and hematopoietic stem cells. Reportedly, high ALDH1A1 expression is found in solitary fibrous tumor (SFT) and hemangiopericytoma (HPC), compared to meningiomas and synovial sarcomas. In combination with CD34, ALDH1A1 may be useful for the differentiation among SFT, HPC, meningioma, and synovial sarcoma.

Printable

Product Properties & Targets

Host

Rabbit

Species Reactivity

Human

Isotype

IgG

Cellular Localization

Axon, Cell projection, Cytoplasm, Cytosol

Gene Name

ALDH1A1

Mol. Weight of Antigen

56kDa

Immunogen

Recombinant fragment (around aa 315-434) of human ALDH1A1 protein (exact sequence is proprietary).

Database Links

Entrez Gene ID

216

Unigene

76392

SwissProt

P00352

Additional Information

Clone

ALDH1A1/7011R

Human Gene Symbol

ALDH1A1

Chromosome Location

9q21.13

Known Applications & Suggested Dilutions

Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 &degC followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

PubMed Links

Storage & Stability

Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.