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Home >> Antibodies >> Sulfotransferase family 1E, estrogen-preferring, member 1

Sulfotransferase family 1E, estrogen-preferring, member 1

Mouse Monoclonal Antibody [Clone CPTC-SULT1E1-1]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

199.00
459.00
459.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

199.00
459.00
459.00
img

Formalin-fixed, paraffin-embedded human Small Intestine stained with SULT1E1 Mouse Monoclonal Antibody (CPTC-SULT1E1-1).

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Formalin-fixed, paraffin-embedded human Lymph Node stained with SULT1E1 Mouse Monoclonal Antibody (CPTC-SULT1E1-1).

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SDS-PAGE Analysis Purified SULT1E1 Mouse Monoclonal Antibody (CPTC-SULT1E1-1). Confirmation of Purity and Integrity of Antibody.

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Western Blot Analysis of liver tissue lysate using SULT1E1 Mouse Monoclonal Antibody (CPTC-SULT1E1-1).

Product Details

Synonyms

EST; EST-1;EST1; Estrogen sulfotransferase; estrogen-preferring; estrone sulfotransferase; ST1E1; STE; Sulfotransferase 1E1; Sulfotransferase ; Sulfotransferase estrogen preferring

Positive Control

Liver tissue lysates. Human liver, intestine or kidney.

Known Applications & Suggested Dilutions

Western Blot, IHC-P         More Details

Western Blot (1-2ug/ml)
Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant full-length human SULT1E1 protein

Cellular Localization

Cytoplasm

Species Reactivity

Human.

Host / Ig Isotype

Mouse / IgG2b, kappa

Mol. Weight of Antigen

35kDa

Specificity & Comments

The soluble sulfotransferases contribute to the elimination of xenobiotics, the activation of procarcinogens and the regulation of hormones by catalyzing the sulfate conjugation of these substances. SULT1E1, also known as STE, is a 294 amino acid member of the SULT1 family. Localized to the cytoplasm and expressed in intestine, liver and kidney, SULT1E1 exists as a homodimer that is thought to control estrogen receptor (ER) levels by sulfurylating free estradiol. Defects in the gene encoding SULT1E1 are associated with an increased risk for endometrial cancer, suggesting a role for SULT1E1 in tumorigenesis.

Related Products



200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Rebbeck, T.R., et al. 2006. J. Natl. Cancer Inst. 98: 1311-1320.
  2. Allali-Hassani, A., et al. 2007. PLoS Biol. 5: e97.

Bioinformatics

  •  Entrez Gene ID: 6783
  •  Gene Symbol: SULT1E1
  •  SwissProt: P49888
  •  Chromosome Location: 14q13.3
  •  Unigene: 479898
NBT02234