Home >> Antibodies >> Proteolipid Protein / Myelin PLP

Proteolipid Protein / Myelin PLP

Mouse Monoclonal Antibody [Clone PLP1/4259]

Printable

Key References

Bioinformatics

Catalog #

Size

20 ug

100 ug

Price (USD)

219.00

499.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml

Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Performance Guarantee

Catalog No

Size

20 ug

100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml

Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

219.00

499.00

Printable

Key References

Bioinformatics

Formalin-fixed, paraffin-embedded human brain stained with Myelin PLP Mouse Monoclonal Antibody (PLP1/4259).

SDS-PAGE Analysis Purified Myelin PLP Mouse Monoclonal Antibody (PLP1/4259). Confirmation of Integrity and Purity of Antibody.

Formalin-fixed, paraffin-embedded human brain stained with Myelin PLP Mouse Monoclonal Antibody (PLP1/4259).

SDS-PAGE Analysis Purified Myelin PLP Mouse Monoclonal Antibody (PLP1/4259). Confirmation of Integrity and Purity of Antibody.

Product Details

Synonyms

Myelin proteolipid protein, PLP, Lipophilin, PLP1, HLD1, SPG2, PMD, Major myelin proteolipid protein (MMPL), DM20

Positive Control

Human brain tissue.

Known Applications & Suggested Dilutions

IHC-P More Details

Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)
(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.

Immunogen

Synthetic peptide GRGTKF that recognizes the C terminal region (aa272-277) of myelin proteolipid protein.

Cellular Localization

Membrane

Species Reactivity

Human, Mouse, Rat, Tenerife Lizard and Cow.

Host / Ig Isotype

Mouse / IgG2a

Mol. Weight of Antigen

23-25kDa

Specificity & Comments

Proteolipid protein (PLP) is the major myelin protein of the CNS and plays an important role in the formation and maintenance of myelin. PLP may play a role in the compaction and stabilization of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in PLP gene can lead to dysmyelinating diseases. Clone PLP1/4259 is used in the detection of PLP by various analysis methods.