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Home >> Antibodies >> Progesterone

Progesterone

Mouse Monoclonal Antibody [Clone 6-5E-10B]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

199.00
429.00
429.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

199.00
429.00
429.00
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SDS-PAGE Analysis Purified Progesterone Mouse Monoclonal Antibody (6-5E-10B). Confirmation of Purity and Integrity of Antibody.

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Molecular Structure of Progesterone

Product Details

Synonyms

Pregn 4 ene 3 20 dione; Pregn 4 ene 3 20 dione

Positive Control

Ovary or Placenta.

Known Applications & Suggested Dilutions

ELISA, IHC, Radioimmnoassay         More Details

ELISA (For coating, order Ab without BSA)
Immunohistochemistry (Not assessed)
Radioimmnoassay (RIA)

Immunogen

Progesterone- 11a-hemisuccinate conjugated to bovine serum albumin (Pr11a-HMS-BSA)

Cellular Localization

Secreted and cytoplasmic

Species Reactivity

All species.

Host / Ig Isotype

Mouse / IgG1, kappa

Mol. Weight of Antigen

314.46Da

Specificity & Comments

This MAb is specific for progesterone. It exhibits minimal cross reactivity with related compounds in ELISA. It reacts with Progesterone-11a-HMS-BSA: 100%; 5-beta-Pregnane-3,20-dione: 48%; 5-alpha-Pregnane-3,20-dione: 26.4%; 17-alpha-Hydroxyprogesterone: 2.5% and 20-alpha-Hydroxyprogesterone: 0.04%. Progesterone is a steroid hormone synthesized from the cholesterol derivative, pregnenolone, in the cortex of the adrenal gland. Progesterone is secreted by the corpus luteum and acts to prepare the endometrium for the implantation of a fertilized egg. During pregnancy, it is secreted by the placenta to prevent spontaneous abortion and to stimulate the development of mammary tissue to produce milk. Thus, progesterone plays a central role in the reproductive events associated with the establishment and maintenance of pregnancy. Luteinized theca cells of normal ovary secrete progesterone. The determination of progesterone concentrations in the body fluids is of great value for endocrinological investigations in women. This MAb may prove useful in identification of ovarian tumors.

Related Products



200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Fantl, V.E., Wang, D.Y., Knyba, R.E. 1982. The production of high affinity monoclonal antibodies to Progesterone. J. Steroid Biochem. 17: 125-130.

Bioinformatics

NBT00237