TAG-72 / CA72.4 (Tumor-Associated Glycoprotein) [CA72/145]

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Summary

Recognizes an oncofetal antigen of 220kDa, identified as a tumor-associated glycoprotein (TAG-72) with properties of a mucin. The majority of human adenocarcinomas including colorectal, pancreatic, gastric, ovarian, endometrial, mammary, and non-small cell lung cancer display some cell populations that are positive for TAG72. About 60% of carcinoma patients express TAG72 in their sera. TAG72 is reportedly useful in distinguishing pulmonary adenocarcinomas from pleural mesotheliomas.

Product Properties & Targets

Host
Applications
Species Reactivity
Isotype
Cellular Localization
N/A
Light Chain
Gene Name
N/A
Positive Control
Breast or lung carcinoma., Jurkat cells
Immunogen
Human CA72.4 protein
Alternate Names
N/A, N/A, CA72.4, Tumor associated glycoprotein 72

Database Links

Entrez Gene ID
Unigene
SwissProt
N/A

Additional Information

Clone
CA72/145
Human Gene Symbol
Not Known
Mol. Weight of Antigen
220kDa

Functions

  • N/A

Known Applications & Suggested Dilutions

  • ELISA (For coating, order Ab without BSA)
  • Optimal dilution for a specific application should be determined.

Key References

  • Lottich SC et. al. Breast Cancer Research and Treatment, 1985, 6(1):49-56.
  • Thor A et. al. Cancer Research, 1986, 46(6):3118-24.

Storage & Stability

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.

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