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Home >> Antibodies >> Mammaglobin (SCGB2A2) (Breast Cancer Marker)

Mammaglobin (SCGB2A2) (Breast Cancer Marker)

Recombinant Mouse Monoclonal Antibody [Clone rMGB/4299]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

219.00
499.00
499.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

219.00
499.00
499.00
img

Formalin-fixed, paraffin-embedded human breast carcinoma stained with Mammaglobin Recombinant Mouse Monoclonal Antibody (rMGB/4299).

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Formalin-fixed, paraffin-embedded human breast carcinoma stained with Mammaglobin Recombinant Mouse Monoclonal Antibody (rMGB/4299).

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SDS-PAGE Analysis Purified Mammaglobin Mouse Monoclonal Antibody (rMGB/4299). Confirmation of Integrity and Purity of Antibody.

Product Details

Synonyms

Mammaglobin-1 (MGB1); Mammaglobin-A; Secretoglobin family 2A member 2 (SCGB2A2); SG2A2; UGB2

Positive Control

HeLa, MCF-7 or T47D cells. Human breast carcinoma.

Known Applications & Suggested Dilutions

IHC-P         More Details

Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)
(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.

Immunogen

Stable CHO cell line producing antibody against Mammaglobin.

Cellular Localization

Cytoplasmic, cell surface and nuclear.

Species Reactivity

Human.

Host / Ig Isotype

Mouse / IgG2a, kappa

Mol. Weight of Antigen

18kDa

Specificity & Comments

Mammaglobin is a 93 amino acid glycoprotein with homology to other secretoglobin-uteroglobin family members. It was originally identified as a breast cancer restricted biomarker by differential screening. Mammaglobin related to secretoglobin family that includes human uteroglobin and lipophilin. Mammaglobin antibody stains cytoplasm of normal breast epithelial cells as well as primary and metastatic breast carcinomas. Mammaglobin expression is absent in prostate, kidney, colon, rectum, small intestine, stomach, pancreas, lung, and thyroid tissues.Mammaglobin may be used as part of an immunohistochemical panel for determination of metastatic breast carcinoma and tumor of unknown primary origin.

Related Products



200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Watson MA., et al.Cancer Res.1999;59:3028 3031.

Bioinformatics

  •  Entrez Gene ID: 4250
  •  Gene Symbol: SCGB2A2
  •  SwissProt: Q13296
  •  Chromosome Location: 11q12.3
  •  Unigene: 46452