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Recombinant Mammaglobin (SCGB2A2) (Breast Cancer Marker) Antibody [MGB/4812R]

In Stock
Catalog Number Formulation Size Price
4250-RBM12-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$229.00
4250-RBM12-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$519.00
4250-RBM12-P1ABX
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
100ug
$519.00
Flat Rate Domestic: $60 | Orders outside the US - Contact Us for Order Information | Ships next business day

Applications & Dilutions

Applications Tested Dillution Protocol Note
Immunohistochemistry (IHC)
1-2ug/ml
30 min at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes

Summary

Mammaglobin, 10 kDa, is a cytoplasmic protein, a mammary-specific member of the uteroglobin family. It is related to a family of epithelial secretory proteins that includes prostatein and Clara cell protein.Mammaglobin occurs in about 80% of breast carcinomas. The extend is generally larger than that of GCDFP-15. Up to 15% of nonbreast carcinomas (such as stomach, lung, colon, hepatobiliary, thyroid, ovarian, and urothelial carcinomas) have been reported positive, usually only focally. Mammaglobin is a sensitive and fairly specific marker for breast carcinoma. The panel should also include Gross cystic disease fluid protein-15 and Estrogen receptor alpha.

Product Properties & Targets

Host
Rabbit
Applications
Species Reactivity
Isotype / Light Chain
IgG / Kappa
Cellular Localization
Secreted
Gene Name
Positive Control
HeLa, MCF-7 or T47D cells. Human breast carcinoma.
Immunogen
Recombinant full-length human Mammaglobin (SCGB2A2) protein
Alternate Names
Mammaglobin-A, Mammaglobin-1, Secretoglobin family 2A member 2, Mammaglobin-1 (MGB1); Mammaglobin-A; Secretoglobin family 2A member 2 (SCGB2A2); SG2A2; UGB2

Database Links

Entrez Gene ID
SwissProt

Additional Information

Clone
MGB/4812R
Chromosome Location
11q12.3
Mol. Weight of Antigen
10.5kDa

Key References

  • Watson MA., et al.Cancer Res.1999;59:3028 3031.

Storage & Stability

Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.

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