2 Union Square, Union City, CA 94587
contact@NeoBiotechnologies.com
510-376-5603

Home >> Antibodies >> Mammaglobin (SCGB2A2) (Breast Cancer Marker)

Mammaglobin (SCGB2A2) (Breast Cancer Marker)

Mouse Monoclonal Antibody [Clone MGB/2000]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

219.00
499.00
499.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

219.00
499.00
499.00
img

Formalin-fixed, paraffin-embedded human breast adenocarcinoma stained with Mammaglobin-Monospecific Mouse Monoclonal Antibody (MGB/2000).

img

Formalin-fixed, paraffin-embedded human breast carcinoma stained with Mammaglobin-Monospecific Mouse Monoclonal Antibody (MGB/2000).

img

SDS-PAGE Analysis Purified Mammaglobin Mouse Monoclonal Antibody (MGB/2000). Confirmation of Integrity and Purity of Antibody.

img

Western Blot Analysis of HeLa, MCF-7, Sk-Br3 & T47D cell lysates using Mouse Mammaglobin-Monospecific Monoclonal Antibody (MGB/2000).

img

Analysis of Protein Array containing >19,000 full-length human proteins using Mammaglobin-Monospecific (SCGB2A2) Mouse Monoclonal Antibody (MGB/2000)

Product Details

Synonyms

Mammaglobin-1 (MGB1); Mammaglobin-A; Secretoglobin family 2A member 2 (SCGB2A2); SG2A2; UGB2

Positive Control

HeLa, MCF-7 or T47D cells. Human breast carcinoma.

Known Applications & Suggested Dilutions

Western Blot, IHC-P         More Details

Western Blot (1-2ug/ml)
Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)
(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant full-length human Mammaglobin (SCGB2A2) protein

Cellular Localization

Cytoplasmic, Cell Surface and Nuclear

Species Reactivity

Human.

Host / Ig Isotype

Mouse / IgG1, kappa

Mol. Weight of Antigen

18kDa

Specificity & Comments

Mammaglobin is a 93 amino acid glycoprotein with homology to other secretoglobin-uteroglobin family members. It was originally identified as a breast cancer restricted biomarker by differential screening. Mammaglobin related to secretoglobin family that includes human uteroglobin and lipophilin. Mammaglobin antibody stains cytoplasm of normal breast epithelial cells as well as primary and metastatic breast carcinomas. Mammaglobin expression is absent in prostate, kidney, colon, rectum, small intestine, stomach, pancreas, lung, and thyroid tissues.Mammaglobin may be used as part of an immunohistochemical panel for determination of metastatic breast carcinoma and tumor of unknown primary origin.

Related Products



200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Watson MA, et al. Mammaglobin expression in primary, metastatic, and occult breast cancer.Cancer Res.1999;59:3028 3031.

Bioinformatics

  •  Entrez Gene ID: 4250
  •  Gene Symbol: SCGB2A2
  •  SwissProt: Q13296
  •  Chromosome Location: 11q12.3
  •  Unigene: 46452