Immunofluorescence staining of K562 cells using LMO2 Recombinant Rabbit Monoclonal Antibody (LMO2/3147R) followed by goat anti-rabbit IgG-CF488 (green). Membrane stained with Phalloidin (Red).
Flow Cytometric Analysis of K562 cells using LMO2 Recombinant Rabbit Monoclonal Antibody (LMO2/3147R); followed by goat anti-rabbit IgG-CF488 (Blue); Isotype Control (Red).
SDS-PAGE Analysis Purified LMO2 Recombinant Rabbit Monoclonal Antibody (LMO2/3147R). Confirmation of Purity and Integrity of Antibody.
Known Applications & Suggested Dilutions
Host / Ig Isotype
Mol. Weight of Antigen
Specificity & Comments
The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. It has a particular function in normal and lymphatic endothelial cells involving the regulation of angiogenesis and lymph-angiogenesis. Immunohistochemical studies have also demonstrated expression of LMO2 in both normal germinal center B-cells and germinal center-derived B-cell lymphomas, including follicular lymphoma and diffuse large B-cell lymphoma. The use of anti-LMO2 is valuable as a tool in the identification of lymphomas of B-cell origin. LMO2 is useful in differentiating follicular lymphoma (LMO2+) from nodal marginal zone lymphoma (LM02-). It also is positive in Hodgkin's and Burkitt's lymphomas.