Home >> Antibodies >> Human Herpes Virus 8 (HHV8)

Human Herpes Virus 8 (HHV8)

Recombinant Rabbit Monoclonal Antibody [Clone HHV8/3633R]

Printable

Key References

Bioinformatics

Catalog #

Size

20 ug

100 ug

Price (USD)

219.00

499.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml

Purified Ab WITHOUT BSA at 1.0mg/ml

Performance Guarantee

Catalog No

Size

20 ug

100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml

Purified Ab WITHOUT BSA at 1.0mg/ml

Price (USD)

219.00

499.00

Printable

Key References

Bioinformatics

SDS-PAGE Analysis Purified HHV8 Recombinant Rabbit Monoclonal Antibody (HHV8/3633R). Confirmation of Purity and Integrity of Antibody.

Formalin-fixed, paraffin-embedded human Kaposi's sarcoma stained with HHV8 Recombinant Rabbit Monoclonal Antibody (HHV8/3633R).

SDS-PAGE Analysis Purified HHV8 Recombinant Rabbit Monoclonal Antibody (HHV8/3633R). Confirmation of Purity and Integrity of Antibody.

Formalin-fixed, paraffin-embedded human Kaposi's sarcoma stained with HHV8 Recombinant Rabbit Monoclonal Antibody (HHV8/3633R).

Product Details

Synonyms

HHV8; Human Herpes Virus 8; Human herpesvirus 8; Kaposi's sarcoma associated herpes virus; KSHV

Positive Control

Kaposi's sarcoma. Cultured cells infected with HHV8.

Known Applications & Suggested Dilutions

ELISA, IF, IHC-P More Details

ELISA (For coating use Ab at 1-5ug/ml, order Ab without BSA)
Immunofluorescence (1-2ug/ml)
Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)
(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant protein corresponding to the latent nuclear antigen 1 molecule of HHV8

Cellular Localization

Nuclear (virus in Kaposi's sarcoma)

Species Reactivity

Species independent

Host / Ig Isotype

Rabbit / IgG

Mol. Weight of Antigen

Not Known

Specificity & Comments

HHV8 encodes a latent nuclear antigen (LNA), which is the product of the viral gene orf 73. LNA is capable of forming a complex with retinoblastoma susceptibility gene product, which may be related to its oncogenic activity. HHV8 is associated with three different diseases observed in AIDS patients; kaposi's sarcoma, primary effusion lymphoma (which is a rare type of non-Hodgkin lymphoma affecting the body cavities) and multicentric Castleman's disease. HHV8 is the likely etiological agent of Kaposi's sarcoma.