Home >> Antibodies >> Hepatocyte Specific Antigen (Hepatocellular Marker)

Hepatocyte Specific Antigen (Hepatocellular Marker)

Mouse Monoclonal Antibody [Clone OCH1E5]

Printable

Key References

Bioinformatics

Catalog #

Size

20 ug

100 ug

Price (USD)

199.00

459.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml

Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Performance Guarantee

Catalog No

Size

20 ug

100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml

Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

199.00

459.00

Printable

Key References

Bioinformatics

Formalin-fixed, paraffin-embedded human Liver stained with Hepatocyte Specific Antigen Mouse Monoclonal Antibody (OCH1E5).

Formalin-fixed, paraffin-embedded human Hepatocellular Carcinoma stained with Hepatocyte Specific Antigen Mouse Monoclonal Antibody (OCH1E5).

SDS-PAGE Analysis Purified Hepatocyte Specific Antigen Mouse Monoclonal Antibody (OCH1E5). Confirmation of Purity and Integrity of Antibody.

Formalin-fixed, paraffin-embedded human Liver stained with Hepatocyte Specific Antigen Mouse Monoclonal Antibody (OCH1E5).

Formalin-fixed, paraffin-embedded human Hepatocellular Carcinoma stained with Hepatocyte Specific Antigen Mouse Monoclonal Antibody (OCH1E5).

SDS-PAGE Analysis Purified Hepatocyte Specific Antigen Mouse Monoclonal Antibody (OCH1E5). Confirmation of Purity and Integrity of Antibody.

Product Details

Synonyms

Not Known

Positive Control

Liver or Hepatocellular Carcinoma (HCC).

Known Applications & Suggested Dilutions

IF, IHC-P More Details

Immunofluorescence (1-2ug/ml)
Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 1mM EDTA, pH 7.5-8.5, for 45 min at 95°C followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Immunogen

Extract of a formalin-fixed, rejected-allograft of a human liver

Cellular Localization

Finely granular cytoplasmic

Species Reactivity

Human. Dog.

Host / Ig Isotype

Mouse / IgG1, kappa

Mol. Weight of Antigen

Not Known

Specificity & Comments

Hepatocyte Specific Antigen, also called Hepatocyte Paraffin 1 or HepPar1, localizes to the mitochondria of hepatocytes. It is a sensitive marker for distinguishing hepatocellular carcinomas (HCC) from other metastatic carcinomas as well as cholangio-carcinomas. HCC's occur primarily in the stomach, but they are also found in many other organs. The Hepatocyte Specific Antigen may also be a useful marker for intestinal metaplasia. Reportedly, strong expression of the Hepatocyte Specific Antigen correlates with smaller tumor size and longer patient survival. Occasionally, Hepatocyte Specific Antigen is also found in gastric carcinomas as well as in a few other non-hepatic tumors.