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Home >> Antibodies >> Galectin-3 (LGALS3) (Thyroid Cell Marker)

Galectin-3 (LGALS3) (Thyroid Cell Marker)

Recombinant Rabbit Monoclonal Antibody [Clone LGALS3/7036R]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

219.00
499.00
499.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

219.00
499.00
499.00
img

SDS-PAGE Analysis Purified LGALS3 Rabbit Recombinant Monoclonal Antibody (LGALS3/7036R). Confirmation of Purity and Integrity of Antibody.

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Formalin-fixed, paraffin-embedded human colon stained with LGALS3 Rabbit Recombinant Monoclonal Antibody (LGALS3/7036R). HIER: Tris/EDTA, pH9.0, 45min. 2: HRP-polymer, 30min. DAB, 5min.

Product Details

Synonyms

35kDa lectin; Carbohydrate-binding protein 35; CBP35; Gal-3; GAL3; Galactose-specific lectin 3; GALBP; Galectin-3; GALIG; GBP; IgE-binding protein; L-34 galactoside-binding lectin; L31; Laminin-binding protein; Lectin L-29; Lectin, galactose binding, soluble 3; LGALS2; LGALS3; MAC2; Macrophage galactose-specific lectin

Positive Control

Human papillary thyroid carcinoma tissue.

Known Applications & Suggested Dilutions

IHC-P         More Details

Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)
(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.

Immunogen

A synthetic peptide from the C-terminus of human LGALS3 protein (aa 150-200) (exact sequence is proprietary)

Cellular Localization

Cytoplasm.

Species Reactivity

Human.

Host / Ig Isotype

Rabbit / IgG, kappa

Mol. Weight of Antigen

26kDa

Specificity & Comments

Galectin-3 is a member of the beta-galactosidase-binding lectin family. It is associated with cell growth, adhesion, inflammation, mRNA processing, and apoptosis. Aberrant expression of Galectin-3 is related to malignant transformation and metastasis in carcinomas of the breast, colon and thyroid.Galectin-3 reactivity can be seen in the nucleus of neutrophils, vascular endothelium, carcinomas of the colon, breast, and thyroid. Galectin-3 may be useful in the differentiationof benign and malignant thyroid neoplasms.Galectin-3 may also be useful in the identification of certain liver disorders.

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200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Bioinformatics

  •  Entrez Gene ID: 3958
  •  Gene Symbol: LGALS3
  •  SwissProt: P17931
  •  Chromosome Location: 14q22.3
  •  Unigene: 531081