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Home >> Antibodies >> Cytokeratin, Acidic (Type I or LMW) (Epithelial Marker)

Cytokeratin, Acidic (Type I or LMW) (Epithelial Marker)

Mouse Monoclonal Antibody [Clone KRTL/1077]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

219.00
499.00
499.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

219.00
499.00
499.00
img

Formalin-fixed, paraffin-embedded human Skin stained with Cytokeratin, LMW Monoclonal Antibody (KRTL/1077).

img

Formalin-fixed, paraffin-embedded Rat Oviduct stained with Cytokeratin, HMW Monoclonal Antibody (KRTL/1077).

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Formalin-fixed, paraffin-embedded Rat Stomach with Cytokeratin, HMW Monoclonal Antibody (KRTL/1077).

Product Details

Synonyms

K1B; KRT1B; K77; CK-1B; Keratin 1B; Keratin-77; Cytokeratin-1B

Positive Control

Skin, Squamous cell carcinoma (SCC).

Known Applications & Suggested Dilutions

IHC-P         More Details

Immunohistochemistry (Formalin-fixed) (0.1-0.2ug/ml for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant human KRT77 protein

Cellular Localization

Cytoplasmic

Species Reactivity

Human. Rat. Shows broad species reactivity.

Host / Ig Isotype

Mouse / IgG1, kappa

Mol. Weight of Antigen

56.5kDa (CK10); 50kDa (CK14); 50kDa (CK15); 48kDa (CK16); 40kDa (CK19)

Specificity & Comments

This MAb recognizes the 56.5kDa (CK10); 50kDa (CK14); 50kDa (CK15); 48kDa (CK16); 40kDa (CK19) keratins of the acidic (Type I or LMW) subfamily. Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. The acidic keratins have molecular weights (MW) of 56.5, 55, 51, 50, 50', 48, 46, 45, and 40kDa. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis.

Related Products



200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Woodock-Mitchell J et. al. Journal of Cell Biology 1982;95:580-8.
  2. Tseng SCG et. al. Cell 1982; 30361.

Bioinformatics

  •  Entrez Gene ID: 374454
  •  Gene Symbol: KRT77
  •  SwissProt: Q7Z794
  •  Chromosome Location: 17q21.2
  •  Unigene: 334989
NBT01077