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Cystatin B (Marker of Epithelial Ovarian Cancer Progression)

Mouse Monoclonal Antibody [Clone CPTC-CSTB-3]

Printable

Key References

Bioinformatics

Catalog #

Size

20 ug

100 ug

Price (USD)

219.00

499.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml

Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Performance Guarantee

Catalog No

Size

20 ug

100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml

Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

219.00

499.00

Printable

Key References

Bioinformatics

SDS-PAGE Analysis Purified Cystatin B Mouse Monoclonal Antibody (CPTC-CSTB-3). Confirmation of Purity and Integrity of Antibody.

Formalin-fixed, paraffin-embedded human lung stained with Cystatin B Mouse Monoclonal Antibody (CPTC-CSTB-3).

SDS-PAGE Analysis Purified Cystatin B Mouse Monoclonal Antibody (CPTC-CSTB-3). Confirmation of Purity and Integrity of Antibody.

Formalin-fixed, paraffin-embedded human lung stained with Cystatin B Mouse Monoclonal Antibody (CPTC-CSTB-3).

Product Details

Synonyms

CHROW21; CPI-B; CST 6; CSTB; CYTB; Stefin B; EPM1; Liver thiol proteinase inhibitor; PME; STFB; ULD

Positive Control

HEK293T or U-87 MG cells. Human tonsil.

Known Applications & Suggested Dilutions

Western Blot, IHC-P More Details

Western Blot (1-2ug/ml)
Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)
(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant full-length human Cystatin B protein

Cellular Localization

Cytoplasm and nucleus.

Species Reactivity

Human.

Host / Ig Isotype

Mouse / IgG1, kappa

Mol. Weight of Antigen

12kDa

Specificity & Comments

Cystatin A (also designated STF1, STFA, stefin A or cystatin AS) and cystatin B (also designated PME, CST6, STFB, CPI-B, stefin B and liver thiol proteinase inhibitor) are thiol protease inhibitors that form complexes with papain and the cathepsins B, H, and L. cystatin A, a cytoplasmic protein, is one of the precursor proteins of the cornified cell envelope in keratinocytes and plays a role in epidermal development and maintenance. cystatin B protects against intracellular proteases leaking out of lysosomes and is primarily expressed in heart, liver and kidney.