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Home >> Antibodies >> Crystallin Alpha B

Crystallin Alpha B

Mouse Monoclonal Antibody [Clone CPTC-CRYAB-1]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

199.00
429.00
429.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

199.00
429.00
429.00
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Formalin-fixed, paraffin-embedded human Breast stained with Crystallin Alpha B Mouse Monoclonal Antibody (CPTC-CYRAB-1).

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Formalin-fixed, paraffin-embedded Rat Heart Muscle stained with Crystallin Alpha B Mouse Monoclonal Antibody (CPTC-CYRAB-1).

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Western Blot Analysis of HeLa cell lysate using Crystallin Alpha B Mouse Monoclonal Antibody (CPTC-CYRAB-1).

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SDS-PAGE Analysis Purified Crystallin Alpha B Mouse Monoclonal Antibody (CPTC-CYRAB-1). Confirmation of Purity and Integrity of Antibody

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Analysis of Protein Array containing more than 19,000 full-length human proteins using Crystallin Alpha B Mouse Monoclonal Antibody (CPTC-CRYAB-1).

Product Details

Synonyms

AACRYA; Alpha B crystallin; Alpha-crystallin B chain; CRYA2; CTTP2; Heat shock 20 kD like protein; Heat shock protein beta-5; HspB5; Renal carcinoma antigen NY REN 27; Rosenthal fiber component

Positive Control

293T whole cell lysates; heart and brain.

Known Applications & Suggested Dilutions

Western Blot, IHC-P         More Details

Western Blot (1-2ug/ml)
Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant human full-length CRYAB protein

Cellular Localization

Cytoplasm, translocates to nucleus during heat shock and resides in nuclear splicing speckles.

Species Reactivity

Human. Rat.

Host / Ig Isotype

Mouse / IgG2c, kappa

Mol. Weight of Antigen

Predicted: 20kDa; Observed: 22-30kDa

Specificity & Comments

Crystallins are the major proteins of the vertebrate eye lens, where they maintain the transparency and refractive index of the lens. Crystallins are divided into B-crystallin is associated with many neurological diseases, and a missense mutation in this gene has co-segregated in a family with a Desmin-related myopathy.

Related Products



200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Haley, D.A., et al. 1998. J. Mol. Biol. 277: 27

Bioinformatics

  •  Entrez Gene ID: 1410
  •  Gene Symbol: CRYAB
  •  SwissProt: P02511
  •  Chromosome Location: 11q23.1
  •  Unigene: 53454
NBT02235