|Catalog No||Formulation||Size||Price (USD)|
|921-MSM8-P0||Purified Ab with BSA and Azide at 200ug/ml||20 ug||199.00|
|921-MSM8-P1||Purified Ab with BSA and Azide at 200ug/ml||100 ug||429.00|
|921-MSM8-P1ABX||Purified Ab WITHOUT BSA and Azide at 1.0mg/ml||100 ug|
|Human Entrez Gene ID||921|
|Human Gene Symbol||CD5|
|Human Chromosome Location||11q12.2|
|Synonyms||CD5 antigen (p56 62), LEU1, Ly12, LyA, Lymphocyte antigen T1/Leu-1, Lymphocyte glycoprotein T1/Leu1, T-cell surface glycoprotein CD5|
|Immunogen||Recombinant fragment of human CD5 protein (around aa 269-366) (exact sequence is proprietary)|
|Host / Ig Isotype||Mouse / IgG2c, kappa|
|Mol. Weight of Antigen||67kDa|
|Cellular Localization||Cell surface|
|Species Reactivity||Human. Others not known.|
Recognizes a 67kDa transmembrane protein, which is identified as CD5. The CD5 antigen is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. Anti-CD5 is a pan T-cell marker that also reacts with a range of neoplastic B-cells, e.g. chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), mantle cell lymphoma, and a subset (~10%) of diffuse large B-cell lymphoma. CD5 aberrant expression is useful in making a diagnosis of mature T-cell neoplasms. Anti-CD5 detection is diagnostic in CLL/SLL within a panel of other B-cell markers, especially one that includes anti-CD23. Anti-CD5 is also very useful in differentiating among mature small lymphoid cell malignancies. In addition, anti-CD5 can be used in distinguishing thymic carcinoma (+) from thymoma (-). Anti-CD5 does not react with granulocytes or monocytes.
Immunohistology (Formalin-fixed) (1-2ug/ml for 30 minutes at RT) (Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes) Optimal dilution for a specific application should be determined.
293T, Ramos, or MOLT-4 Cells. Tonsil.
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
This antibody is available for research use only and is not approved for use in diagnosis.
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.