Formalin-fixed, paraffin-embedded human tonsil stained with CD3e Recombinant Rabbit Monoclonal Antibody (CD3e/4653R) at 2ug/ml. HIER: Tris/EDTA, pH9.0, 45min. 2 °: HRP-polymer, 30min. DAB, 5min.
IHC analysis of formalin-fixed, paraffin-embedded human brain. Negative tissue control using C3e/4653R at 2ug/ml in PBS for 30min RT. HIER: Tris/EDTA, pH9.0, 45min. 2 °: HRP-polymer, 30min. DAB, 5min.
Western Blot Analysis of human Jurkat cell lysate using CD3e Recombinant Rabbit Monoclonal Antibody (C3e/4653R).
Cluster of differentiation 3 (CD3) is a multimeric protein complex, known historically as the T3 complex, and is composed of four distinct polypeptide chains; epsilon ( ), gamma (纬), delta ( �L) and zeta ( �梅), that assemble and function as three pairs of dimers ( 纬, �L, �梅 �梅). The CD3 complex serves as a T cell co-receptor that associates noncovalently with the T cell receptor (TCR).CD3 antigen appearance at all stages of T cell development, and makes it an ideal T cell marker for both the detection of normal T cells and T cell neoplasms (lymphomas and leukemias).
