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Home >> Antibodies >> Tubulin beta 3 / TUBB3 (Neuronal& Stem Cell Marker)

Tubulin beta 3 / TUBB3 (Neuronal& Stem Cell Marker)

Mouse Monoclonal Antibody [Clone TUBB3/3732]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

199.00
459.00
459.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

199.00
459.00
459.00
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SDS-PAGE Analysis. Purified Tubulin beta 3 Mouse Monoclonal Antibody (TUBB3/3732). Confirmation of Purity and Integrity of Antibody.

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Western Blot Analysis of U87 cell lysate using Tubulin beta 3 Mouse Monoclonal Antibody (TUBB3/3732).

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Formalin-fixed, paraffin-embedded human brain stained with Tubulin beta 3 Mouse Monoclonal Antibody (TUBB3/3732).

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Analysis of Protein Array containing more than 21,000 full-length human proteins using Tubulin beta 3 Mouse Monoclonal Antibody (TUBB3/3732)

Product Details

Synonyms

beta 3 tubulin; CDCBM; CDCBM1; CFEOM3; CFEOM3A; FEOM3; M(beta)3; M(beta)6; MC1R; Neuron specific beta III Tubulin; Neuron-specific class III beta-tubulin; TUBB3; TUBB4; Tubulin beta-3; Tubulin beta-4; Tubulin beta-III

Positive Control

U87, A375, Raji orHEP2 cells. Human brain and testis.

Known Applications & Suggested Dilutions

Western Blot, IHC-P         More Details

Western Blot (1-2ug/ml)
Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)
(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.

Immunogen

A synthetic peptide (aa 437-450) of human Tubulin beta 3 protein (TUBB3); coupled to KLH.

Cellular Localization

Cytoplasmic

Species Reactivity

Human. Dog.

Host / Ig Isotype

Mouse / IgG2a, kappa

Mol. Weight of Antigen

55kDa

Specificity & Comments

This gene encodes a class III member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is primarily expressed in neurons and may be involved in neurogenesis and axon guidance and maintenance. Mutations in this gene are the cause of congenital fibrosis of the extraocular muscles type 3.In adults, tubulin beta 3 (TUBB3) is primarily expressed in neurons and is commonly used as a neuronal marker. It plays an important role in neuronal cell proliferation and differentiation.

Related Products



200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Osborn M et. al. European Journal of Cell Biology. 1984; 34:137-143.

Bioinformatics

  •  Entrez Gene ID: 10381
  •  Gene Symbol: TUBB3
  •  SwissProt: Q13509
  •  Chromosome Location: 16q24.3
  •  Unigene: 511743