Western Blot Analysis of kidney tissue lysate using Transthyretin Mouse Monoclonal Antibody (CPTC-TTR-1).
SDS-PAGE Analysis Purified Transthyretin Mouse Monoclonal Antibody (CPTC-TTR-1). Confirmation of Purity and Integrity of Antibody.
Western Blot Analysis of Liver tissue lysate using Transthyretin Mouse Monoclonal Antibody (CPTC-TTR-1).
Analysis of Protein Array containing more than 19,000 full-length human proteins using Transthyretin (Prealbumin) Mouse Monoclonal Antibody (CPTC-TTR-1).
Known Applications & Suggested Dilutions
Host / Ig Isotype
Mol. Weight of Antigen
Specificity & Comments
Prealbumin, also designated transthyretin, is a major thyroid-hormone binding protein involved in transporting thyroxine from the bloodstream to the brain. Prealbumin is located in the cytoplasm and in the vesicles of developing rat brain cells, and is thought to be transported there from the cerebrospinal fluid via endocytosis. Sequence variants of this protein have been identified in amyloid fibrils from patients with familial amyloidotic polyneuropathy (FAP), the most common form of hereditary systemic amyloidosis. Although the biologically active form of Prealbumin is a tetramer, the amyloidogenic intermediate is thought to be a monomeric species. Prealbumin also binds to the retinol carrier protein RBP (retinol-binding protein).