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Home >> Antibodies >> Transthyretin (Prealbumin)

Transthyretin (Prealbumin)

Mouse Monoclonal Antibody [Clone CPTC-TTR-1]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

199.00
459.00
459.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

199.00
459.00
459.00
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Western Blot Analysis of kidney tissue lysate using Transthyretin Mouse Monoclonal Antibody (CPTC-TTR-1).

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SDS-PAGE Analysis Purified Transthyretin Mouse Monoclonal Antibody (CPTC-TTR-1). Confirmation of Purity and Integrity of Antibody.

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Western Blot Analysis of Liver tissue lysate using Transthyretin Mouse Monoclonal Antibody (CPTC-TTR-1).

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Analysis of Protein Array containing more than 19,000 full-length human proteins using Transthyretin (Prealbumin) Mouse Monoclonal Antibody (CPTC-TTR-1).

Product Details

Synonyms

Transthyretin; PALB; HsT2651; prealbumin, amyloidosis type 1; ATTR; TBPA; CTS; CTS1; carpal tunnel syndrome 1; thyroxine-binding prealbumin; prealbumin; HEL111; TTR protein; Epididymis luminal protein 111; prealbumin thyroxine binding; senile systemic amyloidosis antibody

Positive Control

HepG2 cell lysate or human kidney or Liver tissue lysate (WB).

Known Applications & Suggested Dilutions

Western Blot         More Details

Western Blot (1-2ug/ml)
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant human full-length protein

Cellular Localization

Secreted. Cytoplasm.

Species Reactivity

Human.

Host / Ig Isotype

Mouse / IgG2a, kappa

Mol. Weight of Antigen

15kDa

Specificity & Comments

Prealbumin, also designated transthyretin, is a major thyroid-hormone binding protein involved in transporting thyroxine from the bloodstream to the brain. Prealbumin is located in the cytoplasm and in the vesicles of developing rat brain cells, and is thought to be transported there from the cerebrospinal fluid via endocytosis. Sequence variants of this protein have been identified in amyloid fibrils from patients with familial amyloidotic polyneuropathy (FAP), the most common form of hereditary systemic amyloidosis. Although the biologically active form of Prealbumin is a tetramer, the amyloidogenic intermediate is thought to be a monomeric species. Prealbumin also binds to the retinol carrier protein RBP (retinol-binding protein).

Related Products



200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Westermark, P., et al. 2014. Ups. J. Med. Sci. 119: 223-228.

Bioinformatics

  •  Entrez Gene ID: 7276
  •  Gene Symbol: TTR
  •  SwissProt: P02766
  •  Chromosome Location: 18q12.1
  •  Unigene: 427202