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Home >> Antibodies >> Mammaglobin (SCGB2A2) (Breast Cancer Marker)

Mammaglobin (SCGB2A2) (Breast Cancer Marker)

Recombinant Rabbit Monoclonal Antibody [Clone MGB/4812R]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

219.00
499.00
499.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

219.00
499.00
499.00
img

Formalin-fixed, paraffin-embedded human lactating breast stained with Mammaglobin Recombinant Rabbit Monoclonal Antibody (MGB/4812R).

img

Formalin-fixed, paraffin-embedded human lactating breast stained with Mammaglobin Recombinant Rabbit Monoclonal Antibody (MGB/4812R).

img

SDS-PAGE Analysis Purified Mammaglobin Recombinant Rabbit Monoclonal (MGB/4812R). Confirmation of Purity and Integrity of Antibody.

Product Details

Synonyms

Mammaglobin-1 (MGB1); Mammaglobin-A; Secretoglobin family 2A member 2 (SCGB2A2); SG2A2; UGB2

Positive Control

HeLa, MCF-7 or T47D cells. Human breast carcinoma.

Known Applications & Suggested Dilutions

IHC-P         More Details

Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)
(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant full-length human Mammaglobin (SCGB2A2) protein

Cellular Localization

Cytoplasm.

Species Reactivity

Human.

Host / Ig Isotype

Rabbit / IgG, kappa

Mol. Weight of Antigen

10.5kDa

Specificity & Comments

Mammaglobin, 10 kDa, is a cytoplasmic protein, a mammary-specific member of the uteroglobin family. It is related to a family of epithelial secretory proteins that includes prostatein and Clara cell protein.Mammaglobin occurs in about 80% of breast carcinomas. The extend is generally larger than that of GCDFP-15. Up to 15% of nonbreast carcinomas (such as stomach, lung, colon, hepatobiliary, thyroid, ovarian, and urothelial carcinomas) have been reported positive, usually only focally. Mammaglobin is a sensitive and fairly specific marker for breast carcinoma. The panel should also include Gross cystic disease fluid protein-15 and Estrogen receptor alpha.

Related Products



200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Watson MA., et al. Cancer Res. 1999;59:3028-3031.

Bioinformatics

  •  Entrez Gene ID: 4250
  •  Gene Symbol: SCGB2A2
  •  SwissProt: Q13296
  •  Chromosome Location: 11q12.3
  •  Unigene: 46452