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Home >> Antibodies >> Kindlin-2 / KIND2

Kindlin-2 / KIND2

Mouse Monoclonal Antibody [Clone 3A3]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

219.00
499.00
499.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

219.00
499.00
499.00
img

Formalin-fixed, paraffin-embedded human liver stained with KIND2 Mouse Monoclonal Antibody (3A3).

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Formalin-fixed, paraffin-embedded human liver stained with KIND2 Mouse Monoclonal Antibody (3A3).

Product Details

Synonyms

Fermitin family homolog 2 (Fermt2); Kindlin-2 (KIND2); Mitogen-inducible gene 2 protein (MIG2); Pleckstrin homology domain containing family C (with FERM domain) member 1 (PLEKHC1);

Positive Control

293T whole cell lysate. Human tonsil or liver.

Known Applications & Suggested Dilutions

IP, IF, Western Blot, IHC-P         More Details

Immunoprecipitation (1-2ug per 100-500ug of total protein)
Immunofluorescence (1-2ug/ml)
Western Blot (1-2ug/ml)
Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)
(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant protein containing MIG-2 (residues 218-486)

Cellular Localization

Cytoplasm.

Species Reactivity

Human. Mouse. Rat. Bovine. Hamster.

Host / Ig Isotype

Mouse / IgG1, kappa

Mol. Weight of Antigen

78kDa

Specificity & Comments

Kindlin-2 (also known as Mig-2, KIND2) is an important component of cell-extracellular matrix adhesion. Kindlin-2 binds integrins and is involved in ECM adhesion, actin assembly and cell shape modulation. This monoclonal antibody recognizes kindlin-2 in multiple assays including Western blotting, immunoprecipitation, immunohistochemical and immunofluorescent staining.

Related Products



200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Yizeng et al. Cell (2003) 113(1): 37-47

Bioinformatics

  •  Entrez Gene ID: 10979
  •  Gene Symbol: FERMT2
  •  SwissProt: Q96AC1
  •  Chromosome Location: 14q22.1
  •  Unigene: 509343