Home >> Antibodies >> Ferritin, Light Chain (Node-Negative Breast Tumor Prognostic Marker)

Ferritin, Light Chain (Node-Negative Breast Tumor Prognostic Marker)

Recombinant Mouse Monoclonal Antibody [Clone rFTL/1386]

Printable

Key References

Bioinformatics

Catalog #

Size

20 ug

100 ug

Price (USD)

219.00

499.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml

Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Performance Guarantee

Catalog No

Size

20 ug

100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml

Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

219.00

499.00

Printable

Key References

Bioinformatics

Formalin-fixed, paraffin-embedded human kidney stained with Ferritin, Light Chain Recombinant Mouse Monoclonal Antibody (rFTL/1386).

SDS-PAGE Analysis Purified Ferritin, Light Chain Recombinant Mouse MAb (rFTL/1386). Confirmation of Integrity and Purity of Antibody

Western Blot Analysis of human Kidney tissue lysate using Ferritin, Light Chain Mouse Monoclonal Antibody (FTL/1386).

Formalin-fixed, paraffin-embedded human kidney stained with Ferritin, Light Chain Recombinant Mouse Monoclonal Antibody (rFTL/1386).

SDS-PAGE Analysis Purified Ferritin, Light Chain Recombinant Mouse MAb (rFTL/1386). Confirmation of Integrity and Purity of Antibody

Western Blot Analysis of human Kidney tissue lysate using Ferritin, Light Chain Mouse Monoclonal Antibody (FTL/1386).

Product Details

Synonyms

Ferritin L chain; Ferritin L subunit; Ferritin light chain; Ferritin light polypeptide; FTL; LFTD; NBIA3

Positive Control

HepG2, HeLa, HL-60 or 293T cells. Pancreas, Liver, Kidney, Cerebellum or Testis.

Known Applications & Suggested Dilutions

Western Blot, IHC-P More Details

Western Blot (1-2ug/ml)
Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)
(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant full-length human FTL protein

Cellular Localization

Cytoplasmic

Species Reactivity

Human.

Host / Ig Isotype

Mouse / IgG1, kappa

Mol. Weight of Antigen

19-25kDa

Specificity & Comments

Mammalian ferritins consist of 24 subunits made up of 2 types of polypeptide chains, ferritin heavy chain and ferritin light chain. Ferritin heavy chains catalyze the first step in iron storage, the oxidation of Fe (II), whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of Fe (III). Light chain ferritin is involved in cataracts by at least two mechanisms, hereditary hyperferritinemia cataract syndrome, in which light chain ferritin is overexpressed, and oxidative stress, an important factor in the development of ageing-related cataracts.