Formalin-fixed, paraffin-embedded human Breast Carcinoma stained with Ferritin LC Rabbit Recombinant Monoclonal Antibody (FTL/2338R).
SDS-PAGE Analysis Purified Ferritin LC Rabbit Recombinant Monoclonal Antibody (FTL/2338R). Confirmation of Purity and Integrity of Antibody.
Western Blot Analysis of human HeLa cell lysate using Ferritin LC Rabbit Recombinant Monoclonal Antibody (FTL/2338R).
Western Blot Analysis of human kidney tissue lysate using Ferritin LC Rabbit Recombinant Monoclonal Antibody (FTL/2338R).
Mammalian ferritins consist of 24 subunits made up of 2 types of polypeptide chains, ferritin heavy chain and ferritin light chain. Ferritin heavy chains catalyze the first step in iron storage, the oxidation of Fe (II), whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of Fe (III). Light chain ferritin is involved in cataracts by at least two mechanisms, hereditary hyperferritinemia cataract syndrome, in which light chain ferritin is overexpressed, and oxidative stress, an important factor in the development of ageing-related cataracts.
