Home >> Antibodies >> Cytokeratin, Type I (Epithelial Marker)

Cytokeratin, Type I (Epithelial Marker)

Recombinant Rabbit Monoclonal Antibody [Clone KRTL/4440R]

Printable

Key References

Bioinformatics

Catalog #

Size

20 ug

100 ug

Price (USD)

219.00

499.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml

Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Performance Guarantee

Catalog No

Size

20 ug

100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml

Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

219.00

499.00

Printable

Key References

Bioinformatics

Formalin-fixed, paraffin-embedded human skin stained with CK Type I Recombinant Rabbit Monoclonal Antibody (KRTL/4440R).

Formalin-fixed, paraffin-embedded human colon carcinoma stained with CK Type I Recombinant Rabbit Monoclonal Antibody (KRTL/4440R).

Formalin-fixed, paraffin-embedded human colon carcinoma stained with CK Type I Recombinant Rabbit Monoclonal Antibody (KRTL/4440R).

SDS-PAGE Analysis Purified CK Type I Recombinant Rabbit Monoclonal Antibody (KRTL/4440R). Confirmation of Purity and Integrity of Antibody.

Formalin-fixed, paraffin-embedded human skin stained with CK Type I Recombinant Rabbit Monoclonal Antibody (KRTL/4440R).

Formalin-fixed, paraffin-embedded human colon carcinoma stained with CK Type I Recombinant Rabbit Monoclonal Antibody (KRTL/4440R).

SDS-PAGE Analysis Purified CK Type I Recombinant Rabbit Monoclonal Antibody (KRTL/4440R). Confirmation of Purity and Integrity of Antibody.

Product Details

Synonyms

K1B; KRT1B; K77; CK-1B; Keratin 1B; Keratin-77; Cytokeratin-1B

Positive Control

Skin or squamous cell carcinoma.

Known Applications & Suggested Dilutions

IHC-P More Details

Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Immunogen

Synthetic peptide corresponding to Type I Cytokeratins residues within aa100-200 of Type I Cytokeratins

Cellular Localization

Cytoplasmic

Species Reactivity

Human.

Host / Ig Isotype

Rabbit / IgG

Mol. Weight of Antigen

60/53/51/45/40kDa

Specificity & Comments

The keratins are the typical intermediate filament proteins of epithelia, showing an outstanding degree of molecular diversity. Heteropolymeric filaments are formed by pairing of type I and type II molecules. In humans 54 functional keratin genes exist. They are expressed in highly specific patterns related to the epithelial type and stage of cellular differentiation. This antibody can detect high molecular weight CK10, CK14, CK15 and CK16 and low molecular weight CK19. It usually used in a cytokeratin cocktail with type II cytokeratin antibody.