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Home >> Antibodies >> Cystatin A

Cystatin A

Mouse Monoclonal Antibody [Clone CPTC-CSTA-1]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

199.00
459.00
459.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

199.00
459.00
459.00
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Formalin-fixed, paraffin-embedded human Tonsil stained with Cystatin A Mouse Monoclonal Antibody (CPTC-CSTA-1).

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Formalin-fixed, paraffin-embedded human Tonsil stained with Cystatin A Mouse Monoclonal Antibody (CPTC-CSTA-1).

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Formalin-fixed, paraffin-embedded human Prostate Carcinoma stained with Cystatin A Mouse Monoclonal Antibody (CPTC-CSTA-1).

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SDS-PAGE Analysis Purified Cystatin A Mouse Monoclonal Antibody (CPTC-CSTA-1). Confirmation of Purity and Integrity of Antibody

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Western Blot Analysis of THP-1 cell lysate using Cystatin A Mouse Monoclonal Antibody (CPTC-CSTA-1).

Product Details

Synonyms

STF1; STFA; AREI; cstA; Stefin A

Positive Control

THP-1 cells. Human tonsil or prostate tissue (IHC).

Known Applications & Suggested Dilutions

Western Blot, IHC-P         More Details

Western Blot (2-4ug/ml)
Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant full-length human CSTA protein

Cellular Localization

Cell Surface, Cytoplasmic and Nuclear.

Species Reactivity

Human.

Host / Ig Isotype

Mouse / IgG2c, kappa

Mol. Weight of Antigen

11kDa

Specificity & Comments

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins, and kininogens. This gene encodes a stefin that functions as a cysteine protease inhibitor, forming tight complexes with papain and the cathepsins B, H, and L. The protein is one of the precursor proteins of cornified cell envelope in keratinocytes and plays a role in epidermal development and maintenance. Stefins have been proposed as prognostic and diagnostic tools for cancer.

Related Products



200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Takahashi, H., et al. 2001. J. Biol. Chem. 276: 36632-36638

Bioinformatics

  •  Entrez Gene ID: 1475
  •  Gene Symbol: CSTA
  •  SwissProt: P01040
  •  Chromosome Location: 3Q21.1
  •  Unigene: 518198
NBT02236