Formalin-fixed, paraffin-embedded human Tonsil stained with Cdk1 Mouse Monoclonal Antibody (CDK1/873).
SDS-PAGE Analysis Purified Cdk1 Mouse Monoclonal Antibody (CDK1/873). Confirmation of Integrity and Purity of Antibody.
Western Blot Analysis of human HeLa cell lysate using Cdk1 Mouse Monoclonal Antibody (CDK1/873).
Known Applications & Suggested Dilutions
Host / Ig Isotype
Mol. Weight of Antigen
Specificity & Comments
Recognizes a 34kDa protein, which is identified as cyclin dependent kinase 1 (cdk1) or p34cdc2 protein kinase. cdk1 / p34cdc2 plays a crucial role during cell division and is most active during mitosis. It is predominantly localized in the nucleus. It is a serine/threonine kinase, which is activated by cyclin, presumably by de-phosphorylation of tyrosine residues. Activated cdk1 / p34cdc2 performs specific functions during mitosis, including nuclear envelope breakdown and chromosome condensation.