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Home >> Antibodies >> CD81 / TAPA-1

CD81 / TAPA-1

Recombinant Rabbit Monoclonal Antibody [Clone C81/2885R]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

199.00
429.00
429.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

199.00
429.00
429.00
img

Formalin-fixed, paraffin-embedded human Prostate Carcinoma stained with CD81 Rabbit Recombinant Monoclonal Antibody (C81/2885R).

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SDS-PAGE Analysis Purified CD81 Rabbit Recombinant Monoclonal Antibody (C81/2885R). Confirmation of Purity and Integrity of Antibody.

Product Details

Synonyms

CD81; Target of the antiproliferative antibody 1 (TAPA-1); Tetraspanin-28; Tspan-28

Positive Control

Ramos, Daudi or Jurkat cells. Human lymphocytes. Human tonsil or liver.

Known Applications & Suggested Dilutions

ELISA, IHC-P         More Details

ELISA (For coating, order Ab without BSA)
Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant full-length human CD81 protein

Cellular Localization

Cell surface

Species Reactivity

Human. Mouse. Rat.

Host / Ig Isotype

Rabbit / IgG

Mol. Weight of Antigen

26kDa

Specificity & Comments

Recognizes a protein of 26kDa, identified as CD81 (Workshop VI; Code CD81.1)). CD81 has a very broad cellular distribution, being expressed on T- and B-lymphocytes, NK cells, thymocytes, eosinophils, fibroblasts, epithelial and endothelial cells. Neutrophils, erythrocytes and platelets are negative, while monocytes are variably positive. CD81 is a member of a family of tetraspans transmembrane proteins, including CD9, CD37, CD53, CD63, and CD82. It associates with CD19, CD21, Leu 13, and integrins on cell membrane and is involved in signal transduction in B lymphocyte development and cell adhesion. CD81 also acts as a receptor for the envelope protein E2 of chronic hepatitis C virus. Antibodies to CD81 have anti-proliferative effects on different lymphoid cell lines, particularly those derived from large cell lymphomas.

Related Products



200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Kishimoto T et al. eds. Leukocyte Typing VI, p187-189, Garland Publishing, New York, 1997.
  2. Takahashi S et al. J Immunol 1990, 145(7):2207-2213.

Bioinformatics

  •  Entrez Gene ID: 975
  •  Gene Symbol: CD81
  •  SwissProt: P60033
  •  Chromosome Location: 11p15.5
  •  Unigene: 54457
NBT02885