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Formalin-fixed, paraffin-embedded human tonsil stained with CD68 Rabbit Recombinant Monoclonal Antibody (C68/2908R). HIER: Tris/EDTA, pH9.0, 45min. 2°: HRP-polymer, 30min. DAB, 5min.
SDS-PAGE Analysis Purified CD68 Rabbit Recombinant Monoclonal Antibody (C68/2908R). Confirmation of Purity and Integrity of Antibody.
Western Blot Analysis of human spleen tissue lysate using CD68 Rabbit Recombinant Monoclonal Antibody (C68/2908R).
Product Details
Synonyms
Positive Control
Known Applications & Suggested Dilutions
Immunogen
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Mol. Weight of Antigen
Specificity & Comments
This antibody recognizes a glycoprotein of 110kDa, which is identified as CD68. It is important for identifying macrophages in tissue sections. It stains macrophages in a wide variety of human tissues, including Kupffer cells and macrophages in the red pulp of the spleen, in lamina propria of the gut, in lung alveoli, and in bone marrow. It reacts with myeloid precursors and peripheral blood granulocytes. It also reacts with plasmacytoid T cells, which are supposed to be of monocyte/macrophage origin. It shows strong granular cytoplasmic staining of chronic and acute myeloid leukemia and also reacts with rare cases of true histiocytic neoplasia. Lymphomas are negative or show few granules.
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