Home >> Antibodies >> CD268 / BAFFR / TNFRSF13C

CD268 / BAFFR / TNFRSF13C

Mouse Monoclonal Antibody [Clone BAFFR/1558]

Printable

Key References

Bioinformatics

Catalog #

Size

20 ug

100 ug

Price (USD)

219.00

499.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml

Purified Ab WITHOUT BSA at 1.0mg/ml

Performance Guarantee

Catalog No

Size

20 ug

100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml

Purified Ab WITHOUT BSA at 1.0mg/ml

Price (USD)

219.00

499.00

Printable

Key References

Bioinformatics

Formalin-fixed, paraffin-embedded human tonsil stained with CD268 / BAFFR Mouse Monoclonal Antibody (BAFFR/1558).

SDS-PAGE Analysis Purified CD268 / BAFFR Mouse Monoclonal Antibody (BAFFR/1558). Confirmation of Purity and Integrity of Antibody.

Formalin-fixed, paraffin-embedded human tonsil stained with CD268 / BAFFR Mouse Monoclonal Antibody (BAFFR/1558).

SDS-PAGE Analysis Purified CD268 / BAFFR Mouse Monoclonal Antibody (BAFFR/1558). Confirmation of Purity and Integrity of Antibody.

Product Details

Synonyms

TNFRSF13C, BAFFR, BR3, BAFF receptor, BLyS receptor 3, CD268, CD268 antigen, CVID4, Prolixin, BAFF-R, BROMIX

Positive Control

Raji cells. Tonsil and lymph node.

Known Applications & Suggested Dilutions

Flow Cyt, IHC-P More Details

Flow Cytometry (1-2ug/million cells)
Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)
(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant full-length human CD268 protein

Cellular Localization

Cell Surface

Species Reactivity

Human.

Host / Ig Isotype

Mouse / IgG1, kappa

Mol. Weight of Antigen

19kDa (Monomer); 40kDa (Dimer)

Specificity & Comments

Defects in TNFRSF13C are the cause of immunodeficiency common variable type 4 (CVID4) [MIM:613494]; also called antibody deficiency due to BAFFR defect. CVID4 is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B cells is usually in the normal range, but can be low.