Free Shipping in the U.S. for orders over $1000.  Shop Now>>

Printable Datasheet

CD268 / BAFFR / TNFRSF13C Antibody [BAFFR/1558]

In Stock
Catalog Number Formulation Size Price
115650-MSM2-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$249.00
115650-MSM2-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$539.00
115650-MSM2-P1ABX
Purified Ab WITHOUT BSA at 1.0mg/ml
100ug
$539.00
Flat Rate Domestic: $75 | Orders outside the US - Contact Us for Order Information | Ships next business day
CD268 / BAFFR / TNFRSF13C Antibody

Formalin-fixed, paraffin-embedded human tonsil stained with CD268 / BAFFR Mouse Monoclonal Antibody (BAFFR/1558).

CD268 / BAFFR / TNFRSF13C Antibody - Image 2

SDS-PAGE Analysis of Purified CD268 / BAFFR Mouse Monoclonal Antibody (BAFFR/1558). Confirmation of Purity and Integrity of Antibody.

Applications & Dilutions

Applications Tested Dillution Protocol Note
Flow Cytometry (Flow)
1-2ug/million cells
Flow Cytometry Protocol
Immunohistochemistry (IHC)
1-2ug/ml
IHC Protocol
30 min at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes

Summary

Defects in TNFRSF13C are the cause of immunodeficiency common variable type 4 (CVID4) [MIM:613494]; also called antibody deficiency due to BAFFR defect. CVID4 is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B cells is usually in the normal range, but can be low.

Product Properties & Targets

Antibody Type
Mouse Monoclonals
Host
Mouse
Applications
Flow Cytometry, Immunohistochemistry
Species Reactivity
Human
Research Areas
Immunology, AKT Signaling, B Cell Markers, Cytokine Signaling
Isotype / Light Chain
IgG1 / Kappa
Cellular Localization
Membrane
Gene Name
TNFRSF13C
Positive Control
Raji cells. Tonsil and lymph node.
Immunogen
Recombinant full-length human CD268 protein
Alternate Names
Tumor necrosis factor receptor superfamily member 13C, B-cell-activating factor receptor, BAFF receptor, BLyS receptor 3, TNFRSF13C, BAFFR, BR3, BAFF receptor, BLyS receptor 3, CD268, CD268 antigen, CVID4, Prolixin, BAFF-R, BROMIX

Database Links

Entrez Gene ID
115650
SwissProt
Q96RJ3

Additional Information

Clone
BAFFR/1558
Chromosome Location
22q13.2
Mol. Weight of Antigen
19kDa (Monomer); 40kDa (Dimer)

Related Antibodies

View All TNFRSF13C Antibodies

Functions

  • B-cell receptor specific for TNFSF13B/TALL1/BAFF/BLyS. Promotes the survival of mature B-cells and the B-cell response.

Key References

  • Thompson, J S, C Ambrose, et al. (2001) Science 293(5537): 2108-2111.
  • G Fazio, G Cazzaniga, et al. (2017) BJH.

PubMed Links

Storage & Stability

Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab purified from rabbit anti-serum by Protein A. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.

Reviews

There are no reviews yet.

Be the first to review “CD268 / BAFFR / TNFRSF13C Antibody”

Your email address will not be published. Required fields are marked *

PARTNERSHIP OPPORTUNITIES

NeoBiotechnologies holds Exclusive rights to 10,000 recombinant and hybridoma antibody products, available for Licensing or Collaboration.

LETS TALK
Call Us Now: 1-866-2-NEOBIO (1-866-263-6246)
NeoBiotechnologies Logo
Company Info
Antibodies
Antibody Validation
Research Areas
Resources
Newsletter Signup Updates & Sales