Formalin-fixed, paraffin-embedded kidney stained with CD137 Recombinant Rabbit Monoclonal Antibody (4-1BB/4552R).
Formalin-fixed, paraffin-embedded human kidney stained with CD137 Recombinant Rabbit Monoclonal Antibody (4-1BB/4552R).
Western Blot Analysis of kidney tissue lysate using CD137 Recombinant Rabbit Monoclonal Antibody (4-1BB/4552R).
Known Applications & Suggested Dilutions
Host / Ig Isotype
Mol. Weight of Antigen
Specificity & Comments
CD137 belongs to the tumor necrosis factor receptor family and delivers a costimulatory signal to T lymphocytes. It is expressed on activated T cells and binds an inducible ligand that is found on B cells, macrophages and dendritic cells. Interactions between CD137 and its ligand are involved in antigen presentation and the generation of cytotoxic T cells. CD137 antibody may improve cancer treatment, and has been implicated in breast cancer, melanoma and lymphoma.