Home >> Antibodies >> CD103 / Integrin αEβ7 (T-Cell Lymphoma & Hairy Cell Leukemia Marker)

CD103 / Integrin αEβ7 (T-Cell Lymphoma & Hairy Cell Leukemia Marker)

Recombinant Mouse Monoclonal Antibody [Clone rITGAE/2063]

Printable

Key References

Bioinformatics

Catalog #

Size

20 ug

100 ug

Price (USD)

219.00

499.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml

Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Performance Guarantee

Catalog No

Size

20 ug

100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml

Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

219.00

499.00

Printable

Key References

Bioinformatics

Formalin-fixed, paraffin-embedded human Tonsil stained with CD103 Recombinant Mouse Monoclonal Antibody (rITGAE/2063).

SDS-PAGE Analysis Purified CD103 Recombinant Mouse Monoclonal Antibody (rITGAE/2063). Confirmation of Purity and Integrity of Antibody.

Formalin-fixed, paraffin-embedded human Tonsil stained with CD103 Recombinant Mouse Monoclonal Antibody (rITGAE/2063).

SDS-PAGE Analysis Purified CD103 Recombinant Mouse Monoclonal Antibody (rITGAE/2063). Confirmation of Purity and Integrity of Antibody.

Product Details

Synonyms

CD103; Human mucosal lymphocyte antigen 1 (HML1 antigen); Integrin alpha E heavy chain; Integrin alpha E light chain; Integrin alpha E, epithelial-associated; Integrin alpha E1; Integrin alpha-IEL (intestinal intraepithelial lymphocytes); Integrin alpha M290; Integrin alpha-E heavy chain; Integrin, alpha E (ITGAE)

Positive Control

Human tonsil, colon or stomach tissue (IHC).

Known Applications & Suggested Dilutions

IHC-P More Details

Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)
(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant human ITGAE/CD103 protein fragment (aa 775-855) (exact sequence is proprietary)

Cellular Localization

Cell surface and cytoplasm

Species Reactivity

Human.

Host / Ig Isotype

Mouse / IgG1, kappa

Mol. Weight of Antigen

150kDa

Specificity & Comments

This MAb recognizes a protein of 150kDa, identified as CD103, which is the alpha-E integrin subunit of the heterodimeric alpha-E beta-7 (aEb7) integrin belonging to a small beta-7 integrin subfamily. CD103 is expressed on more than 95% of intraepithelial CD8+ cells and on 40% of mucosa-associated T cells, whereas less than 2% of resting blood lymphocytes are CD103-positive. In several malignant conditions, such as T-cell lymphomas and hairy cell leukemia (HCL), the cells express CD103. Antibody to CD103 is an extremely useful addition to the IHC panel for the diagnosis of hairy cell leukemia (HCL).