Formalin-fixed, paraffin-embedded human liverstained with Apolipoprotein B Mouse Monoclonal Antibody (APOB/3300).
Formalin-fixed, paraffin-embedded human liver stained with Apolipoprotein B Mouse Monoclonal Antibody (APOB/3300).
SDS-PAGE Analysis PurifiedApolipoprotein B Mouse Monoclonal Antibody (APOB/3300). Confirmation of Purity and Integrity of Antibody.
Analysis of Protein Array containing more than 19,000 full-length human proteins using Apolipoprotein B Mouse Monoclonal Antibody (APOB/3300).
Known Applications & Suggested Dilutions
Host / Ig Isotype
Mol. Weight of Antigen
Specificity & Comments
Post-transcriptional editing of apolipoprotein B (apoB) mRNA is regulated byAPOBEC1 (also designated human (or rat) small intestinal apolipoprotein BmRNA editing protein, HEPR or REPR) in hepatic cells to achieve a steadystate proportion of edited and unedited RNA molecules. Two forms of apoBare known to circulate in the plasma of mammals. ApoB-100 is a proteinprimarily synthesized in the liver as a structural component of very low densitylipoprotein particles. A truncated form of apoB-100, apoB-48, is synthesizedin the small intestine and contains the amino-terminal 2,152 amino acids ofthe larger protein. This organ-specific partitioning of apoB production is theresultof RNA editing of a common apoB gene.