SDS-PAGE Analysis Purified CD3e Hamster Monoclonal Antibody (145-2C11).

CD3e, Mouse [145-2C11]

Clear

Summary

CD3 chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex. The 145-2C11 antibody is useful forin vitroblocking and activation assays, as well as apoptosis induction andin vivoT cell depletion.

Product Properties & Targets

Host
Armenian Hamster
Species Reactivity
Mouse
Isotype
IgG
Cellular Localization
Cell membrane
Gene Name
CD3E
Mol. Weight of Antigen
23kDa
Immunogen
H2Kb specific Mouse cytotoxic T lymphocyte clone BM10 37

Database Links

Entrez Gene ID
12501
Unigene
210361
SwissProt
P22646

Additional Information

Clone
145-2C11
Human Gene Symbol
Cd3e (Mouse)
Chromosome Location
9 A5.2; 9 24.84 cM (Mouse)

Known Applications & Suggested Dilutions

  • Functional Studies (Order Antibody without BSA & Azide)
  • Flow Cytometry (0.5-1ug/million cells in 0.1ml)
  • Immunofluorescence (1-2ug/ml)
  • Optimal dilution for a specific application should be determined.

Key References

  • Leo O, et al. 1987. P. Natl. Acad. Sci. USA 84:1374. (IP, Activation)
  • Salvadori S, et al. 1994. J. Immunol. 153:5176. (WB)
  • Henrickson M, et al. 1995. Transplantation 60:828. (Deplete)
  • Payer E, et al. 1991. J. Immunol. 146:2536. (IF)
  • Miescher GC, et al. 1989. Immunol. Lett. 23:113. (Block)
  • Wang W, et al. 2007. J. Immunol. 178:4885. (Activation)
  • Podd BS, et al. 2006. J. Immunol. 176:6532. (IHC)

PubMed Links

Storage & Stability

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.

Related products

Recombinant mouse monoclonal antibodies and recombinant rabbit monoclonals to support your research

Shop Primary Antibodies

Company Info
Antibodies
View All
Hosts
View All
Isotype
View All
Newsletter Signup NeoBiotechnologies Updates & Sales

$0.00
510-376-5603