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Home >> Antibodies >> Retinol Binding Protein-1 (RBP1)

Retinol Binding Protein-1 (RBP1)

Recombinant Mouse Monoclonal Antibody [Clone rRBP1/872]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

199.00
459.00
459.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

199.00
459.00
459.00
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SDS-PAGE Analysis Purified RBP1 Recombinant Mouse Monoclonal Antibody (rRBP1/872). Confirmation of Purity and Integrity of Antibody.

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Formalin-fixed, paraffin-embedded human Hepatocellular Carcinoma stained with RBP1 Recombinant Mouse Monoclonal Antibody (rRBP1/872).

Product Details

Synonyms

Cellular retinol-binding protein I, CRBP1, CRBP2, RBP1, RBP2, RBP4, RBPC, Retinol binding protein 1, Retinol binding protein 1 cellular, Retinol binding protein 2 cellular, Retinol binding protein 4 plasma

Positive Control

Human Hepatic or Ovarian Carcinoma tissues (IHC).

Known Applications & Suggested Dilutions

IHC-P         More Details

Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant full-length human RBP protein

Cellular Localization

Cytoplasmic

Species Reactivity

Human. Chimpanzee. Monkey. Goat. Rabbit. Rat. Mouse.

Host / Ig Isotype

Mouse / IgG1, kappa

Mol. Weight of Antigen

21-25kDa

Specificity & Comments

This MAb recognizes an epitope within the 74-182 C-terminal sequence (11kD peptide fragment) of human serum Cellular Retinol Binding Protein 1 (CRBP 1), a single-chain glycoprotein belonging to the superfamily of hydrophobic molecule transporter proteins, which is responsible for transport of retinol (vitamin A1) from the liver to peripheral target tissues, like the eye, where it mediates the cellular uptake. CRBP 1 is synthesized by hepatic parenchymal cells where it becomes bound to its ligand retinol and is then released into the circulation, where it binds further to the protein transthyretin, to form a transporting complex, which is big enough not to be lost by filtration through the kidney glomeruli. It is detected in nearly all tissues with higher expression in adult ovary, pancreas, pituitary gland, adrenal gland, and fetal liver.

Related Products



200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Reddy BM et al. Molecular Immunology, 1993, 30(15):1355-60.
  2. Reddy B. et al.: Biochem. Int. 21, 367-376 (1990).
  3. Reddy B. et al.: Molec. Immunol. 29, 511-516 (1992).

Bioinformatics

NBT03603