Home >> Antibodies >> Retinol Binding Protein-1 (RBP1)

Retinol Binding Protein-1 (RBP1)

Mouse Monoclonal Antibody [Clone RBP/872]

Printable

Key References

Bioinformatics

Catalog #

Size

20 ug

100 ug

Price (USD)

219.00

499.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml

Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Performance Guarantee

Catalog No

Size

20 ug

100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml

Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

219.00

499.00

Printable

Key References

Bioinformatics

Formalin-fixed, paraffin-embedded human Hepatocellular Carcinoma stained with RBP1 (RBP/872)

Formalin-fixed, paraffin-embedded human Ovarian Carcinoma stained with RBP1 (RBP/872)

Formalin-fixed, paraffin-embedded human Hepatocellular Carcinoma stained with RBP1 (RBP/872)

Formalin-fixed, paraffin-embedded human Ovarian Carcinoma stained with RBP1 (RBP/872)

Product Details

Synonyms

Cellular retinol-binding protein I, CRBP1, CRBP2, RBP1, RBP2, RBP4, RBPC, Retinol binding protein 1, Retinol binding protein 1 cellular, Retinol binding protein 2 cellular, Retinol binding protein 4 plasma

Positive Control

Hepatic or ovarian carcinoma.

Known Applications & Suggested Dilutions

IHC-P More Details

Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant human retinol binding protein-1 (RBP1)

Cellular Localization

Cytoplasmic

Species Reactivity

Human. Monkey. Goat. Rabbit. Rat. Mouse.

Host / Ig Isotype

Mouse / IgG1, kappa

Mol. Weight of Antigen

21-25kDa

Specificity & Comments

Recognizes a protein of 21kDa-25kDa, identified as retinol binding protein-1 (RBP1). This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin, which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein post-transnationally and results in defective delivery and supply to the epidermal cells.