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Home >> Antibodies >> Retinol Binding Protein-1 (RBP1)

Retinol Binding Protein-1 (RBP1)

Mouse Monoclonal Antibody [Clone RBP/872]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

199.00
459.00
459.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

199.00
459.00
459.00
img

Formalin-fixed, paraffin-embedded human Hepatocellular Carcinoma stained with RBP1 (RBP/872)

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Formalin-fixed, paraffin-embedded human Ovarian Carcinoma stained with RBP1 (RBP/872)

Product Details

Synonyms

Cellular retinol-binding protein I, CRBP1, CRBP2, RBP1, RBP2, RBP4, RBPC, Retinol binding protein 1, Retinol binding protein 1 cellular, Retinol binding protein 2 cellular, Retinol binding protein 4 plasma

Positive Control

Hepatic or ovarian carcinoma.

Known Applications & Suggested Dilutions

IHC-P         More Details

Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant human retinol binding protein-1 (RBP1)

Cellular Localization

Cytoplasmic

Species Reactivity

Human. Monkey. Goat. Rabbit. Rat. Mouse.

Host / Ig Isotype

Mouse / IgG1, kappa

Mol. Weight of Antigen

21-25kDa

Specificity & Comments

Recognizes a protein of 21kDa-25kDa, identified as retinol binding protein-1 (RBP1). This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin, which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein post-transnationally and results in defective delivery and supply to the epidermal cells.

Related Products



200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Naylor, H.M., et al. 1999. The structure of human retinol-binding protein (RBP) with its carrier protein transthyretin reveals an interaction with the carboxy-terminus of RBP. Biochemistry 38: 2647-2653.

Bioinformatics

NBT00872