Formalin-fixed, paraffin-embedded human Endometrial Carcinoma stained with Progesterone Receptor Mouse Monoclonal Antibody (PGR/2694).
SDS-PAGE Analysis Purified Progesterone Receptor Mouse Monoclonal Antibody (PGR/2694). Confirmation of Purity and Integrity of Antibody.
Analysis of Protein Array containing more than 19,000 full-length human proteins using Progesterone Receptor Mouse Monoclonal Antibody (PGR/2694).
Known Applications & Suggested Dilutions
Host / Ig Isotype
Mol. Weight of Antigen
Specificity & Comments
This MAb is specific to progesterone receptor and shows minimal cross-reaction with other members of the family. Progesterone receptor is expressed as two major isoforms, PR-A (81kDa) and PR-B (116kDa). Expression of PgR has been suggested to reflect a intact estrogen regulatory machinery and therefore, predict better clinical response to endocrine therapy than estrogen receptor (ER) alone. This MAb is excellent for immunohistochemical staining of formalin-fixed tissues.