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Home >> Antibodies >> Plakophilin-1 (PKP1)

Plakophilin-1 (PKP1)

Mouse Monoclonal Antibody [Clone 10B2]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

199.00
459.00
459.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

199.00
459.00
459.00
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Western Blot of U87, HeLa and A431 cell lysates using Plakophilin-1 Mouse Monoclonal Antibody (10B2)

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SDS-PAGE Analysis Purified CD56 Monoclonal Antibody (NCAM1/784). Confirmation of Integrity and Purity of Antibody

Product Details

Synonyms

B6P; Band 6 protein; PKP1; Plakophilin-1 (ectodermal dysplasia/skin fragility syndrome)

Positive Control

U87, HeLa and A431 cells.

Known Applications & Suggested Dilutions

Flow Cyt, IF, Western Blot         More Details

Flow Cytometry (1-2ug/million cells)
Immunofluorescence (1-2ug/ml)
Western Blot (1-2ug/ml)
Optimal dilution for a specific application should be determined.

Immunogen

N-terminus of human Plakophilin-1 protein

Cellular Localization

Cell Surface and nuclear

Species Reactivity

Human. Mouse.

Host / Ig Isotype

Mouse / IgG1, kappa

Mol. Weight of Antigen

75kDa

Specificity & Comments

Recognizes a protein of 75kDa, identified as Plakophilin-1. Its epitope maps between aa 1-27 human Plakophilin-1. Plakophilins 1, 2, 3 and 4 (PKP1-4) influence development and participate in linking cadherins to cytoskeletal intermediate filaments. Plakophilins 1-4 contain arm-repeat (armadillo) domains and localize to nuclei and cell desmosomes (cell-cell junctions found in suprabasal layers of stratifying epithelia that undergo mechanical stress). Plakophilin 2 is important for desmosome assembly and is an essential morphogenic factor and architectural component of the heart.

Related Products



200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Hadiji-Abbes, N. et al. 2014. Negative control glucose dependent mediated by the PreS2 region on the translation efficiency of the reporter Sh-bleomycin gene in Saccharomyces cerevisiae. FEMS Yeast Res. 14: 357-63.

Bioinformatics

  •  Entrez Gene ID: 5317
  •  Gene Symbol: PKP1
  •  SwissProt: Q13835
  •  Chromosome Location: 1q32
  •  Unigene: 497350
NBT01441