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Home >> Antibodies >> PAX5 / BSAP (Early B-Cell Marker)

PAX5 / BSAP (Early B-Cell Marker)

Recombinant Mouse Monoclonal Antibody [Clone rPAX5/2060]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

199.00
459.00
459.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

199.00
459.00
459.00
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Western Blot Analysis of human Raji cell lysate using PAX5 Mouse Recombinant Monoclonal Antibody (rPAX5/2060).

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SDS-PAGE Analysis Purified PAX5 Mouse Recombinant Monoclonal Antibody (rPAX5/2060). Confirmation of Purity and Integrity of Antibody.

Product Details

Synonyms

B cell lineage specific activator; BSAP; EBB-1; KLP; Paired box 5

Positive Control

Daudi or Ramos cells. Tonsil, spleen, Lymph Nodeor Colon Carcinoma.

Known Applications & Suggested Dilutions

ELISA, Western Blot         More Details

ELISA (For coating, purchase antibody without BSA)
Western Blot (1-2ug/ml)
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant full-length humanPAX5 protein

Cellular Localization

Nuclear

Species Reactivity

Human.

Host / Ig Isotype

Mouse / IgG1, kappa

Mol. Weight of Antigen

42kDa

Specificity & Comments

The specificity of this monoclonal antibody to its intended target was validated by HuProtTM Array, containing more than 19,000, full-length human proteins. The PAX5 gene is a member of thepaired box (PAX)family of transcription factors. The central feature of this gene family is a novel, highly conservedDNA-binding domain, known as thepaired box. The PAX proteins are important regulators in early development, and alterations in the expression of their genes are thought to contribute toneoplastic transformation. The PAX5 gene encodes theB-celllineage specific activator protein (BSAP) that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis; therefore, PAX5 gene product may not only play an important role in B-cell differentiation, but also in neural development andspermatogenesis.

Related Products



200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Desouki MM, Post GR, Cherry D, Lazarchick J. PAX-5: a valuable immunohistochemical marker in the differential diagnosis of lymphoid neoplasms. Clin Med Res. 2010 Jul;8(2):84-8.

Bioinformatics

  •  Entrez Gene ID: 5079
  •  Gene Symbol: PAX5
  •  SwissProt: Q02548
  •  Chromosome Location: 9p13.2
  •  Unigene: 654464
NBT02301