Home >> Antibodies >> MRP1 / ABCC1 (Multidrug Resistance Related Protein 1)

MRP1 / ABCC1 (Multidrug Resistance Related Protein 1)

Mouse Monoclonal Antibody [Clone MRP1/1344]

Printable

Key References

Bioinformatics

Catalog #

Size

20 ug

100 ug

Price (USD)

219.00

499.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml

Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Performance Guarantee

Catalog No

Size

20 ug

100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml

Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

219.00

499.00

Printable

Key References

Bioinformatics

Product Details

Synonyms

ABC29; ABCC1; ATP binding cassette sub family C (CFTR/MRP) member 1; ATP-binding cassette sub-family C member 1; GSX; Leukotriene C(4) transporter; LTC4 transporter; Multidrug resistance-associated protein 1 (MRP1)

Positive Control

A549 cells. Colon, Endometrium, Ovary. Testis or Tonsil.

Known Applications & Suggested Dilutions

Flow Cyt, IF More Details

Flow Cytometry (1-2ug/million cells)
Immunofluorescence (1-2ug/ml)
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant full-length human ABCC1 protein

Cellular Localization

Cytoplasmic and Cell Surface

Species Reactivity

Human.

Host / Ig Isotype

Mouse / IgG2a, kappa

Mol. Weight of Antigen

190kDa

Specificity & Comments

The two members of the large family of ABC transporters known to confer multidrug resistance in human cancer cells are the MDR1 P-glycoprotein and the multidrug-resistance protein MRP1. MRP1 is an integral membrane protein that contains an MDR-like core, an N-terminal membrane-bound region and a cytoplasmic linker, and it is expressed in various cerebral cells, as well as in lung, testis and peripheral blood.