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Home >> Antibodies >> Interferon gamma (IFNG)

Interferon gamma (IFNG)

Recombinant Rabbit Monoclonal Antibody [Clone IFNG/3996R]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

219.00
499.00
499.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

219.00
499.00
499.00
img

Formalin-fixed, paraffin-embedded human pancreas stained with Interferon gamma Recombinant Rabbit Monoclonal Antibody (IFNG/3996R). HIER: Tris/EDTA, pH9.0, 45min. 2: HRP-polymer, 30min. DAB, 5min.

img

Formalin-fixed, paraffin-embedded human kidney stained with Interferon gamma Recombinant Rabbit Monoclonal Antibody (IFNG/3996R). HIER: Tris/EDTA, pH9.0, 45min. 2: HRP-polymer, 30min. DAB, 5min.

img

Formalin-fixed, paraffin-embedded human kidney stained with Interferon gamma Recombinant Rabbit Monoclonal Antibody (IFNG/3996R).

Product Details

Synonyms

AMCF1; Beta thromboglobulin like protein; CXC chemokine ligand 8 (CXCL8); Emoctakin; Granulocyte chemotactic protein 1 (GCP1); IFG; IFI; IFN Immune; Interleukin 8; LECT; LUCT; Lymphocyte derived neutrophil activating factor; LYNAP; Macrophage Activating Factor (MAF); Monocyte derived neutrophil activating protein (MONAP); Monocyte derived neutrophil chemotactic factor (MDNCF); Neutrophil activating factor (NAF); Neutrophil activating peptide 1 (NAP1); Neutrophil activating protein 1 (NAP1); SCYB8; T cell chemotactic factor; T Cell Interferon

Positive Control

PMA stimulated human peripheral blood mononuclear cells. Renal or testicular carcinoma.

Known Applications & Suggested Dilutions

IHC-P         More Details

Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)
(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant full-length human IFNG protein

Cellular Localization

Cytoplasm. Cell surface.

Species Reactivity

Human.

Host / Ig Isotype

Rabbit / IgG, kappa

Mol. Weight of Antigen

20-25kDa

Specificity & Comments

Recognizes a protein of 20-25kDa, identified as human interferon. This MAb is specific to human IFN-γ and recognizes both recombinant and native human IFN-gamma. T lymphocytes and NK cells mainly produce IFN-γ. It is a pleiotropic cytokine involved in the regulation of nearly all phases of immune and inflammatory responses, including the activation, growth and differentiation of T cell, B cells, macrophages, NK cells and other cell types such as endothelial cells and fibroblasts. It has weak anti-viral and anti-proliferative activity, and potentiates the antiviral and anti-tumor effects of IFN-α/β (type I interferon).

Related Products



200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Vilcek J. Cytokine Growth Factor Rev 1997,8(4):239
  2. Farrar MA and Schreiber RD. Annu Rev Immunol 1993, 11:571-611
  3. Vilcek J., et al. Methods Enzymol 1986,119:48-54

Bioinformatics

  •  Entrez Gene ID: 3458
  •  Gene Symbol: IFNG
  •  SwissProt: P01579
  •  Chromosome Location: 12q14
  •  Unigene: 856