Formalin-fixed, paraffin-embedded human Breast Carcinoma stained with Heregulin-1 Mouse Monoclonal Antibody (NRG1/2710).
SDS-PAGE Analysis Purified Heregulin-1 Mouse Monoclonal Antibody (NRG1/2710). Confirmation of Purity and Integrity of Antibody.
Analysis of Protein Array containing more than 19,000 full-length human proteins using Heregulin-1 Mouse Monoclonal Antibody (NRG1/2710).
Known Applications & Suggested Dilutions
Host / Ig Isotype
Mol. Weight of Antigen
Specificity & Comments
Heregulin-1 is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are expressed in a tissue-specific manner and differ significantly in their structure, and are classified as types I, II, III, IV, V and VI. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD).