Home >> Antibodies >> HER-2 / c-erbB-2 / neu / CD340

HER-2 / c-erbB-2 / neu / CD340

Mouse Monoclonal Antibody [Clone HRB2/273]

Printable

Key References

Bioinformatics

Catalog #

Size

20 ug

100 ug

Price (USD)

219.00

499.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml

Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Performance Guarantee

Catalog No

Size

20 ug

100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml

Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

219.00

499.00

Printable

Key References

Bioinformatics

SDS-PAGE Analysis Purified HER-2 Mouse Monoclonal Antibody (HRB2/273). Confirmation of Integrity and Purity of Antibody.

Immunofluorescent staining of MCF-7 cells with HER-2 Mouse Monoclonal Antibody (HRB2/273) followed by goat anti-Mouse IgG-CF488 (Green). Nuclei are stained with Reddot (Red).

SDS-PAGE Analysis Purified HER-2 Mouse Monoclonal Antibody (HRB2/273). Confirmation of Integrity and Purity of Antibody.

Immunofluorescent staining of MCF-7 cells with HER-2 Mouse Monoclonal Antibody (HRB2/273) followed by goat anti-Mouse IgG-CF488 (Green). Nuclei are stained with Reddot (Red).

Product Details

Synonyms

p185, CD340, Verb b2 Erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/Glioblastoma Derived Oncogene Homolog

Positive Control

MCF-7, SKBR-3 cells. Breast Cancers.

Known Applications & Suggested Dilutions

ELISA, Flow Cyt, IF More Details

ELISA (For coating, order antibody without BSA)
Flow Cytometry (1-2ug/million cells)
Immunofluorescence (1-2ug/ml)
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant extracellular domain of human HER-2 protein

Cellular Localization

Cell Surface

Species Reactivity

Human.

Host / Ig Isotype

Mouse / IgG1, kappa

Mol. Weight of Antigen

185kDa

Specificity & Comments

This MAb is specific to c-erbB-2/HER-2 and shows minimal cross-reaction with other members of the family. C-erbB-2/HER-2 is a member of the EGFR family. Receptors of this family are located on the plasma membrane and consist of an extracellular ligand-binding domain that is connected to a large intracellular domain by a single transmembrane sequence. c-erbB-2/HER-2 protein is over-expressed in a variety of carcinomas especially those of breast and ovary.